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Opioids

Anxiety sensitivity and substance use: Differential levels across individuals primarily using opioids, cannabis, or stimulants.

Jan 28, 2021

The purpose of the current study was to compare levels of anxiety sensitivity (AS) across a treatment-seeking sample of individuals primarily using opioids, stimulants, or cannabis. Consistent with th...

Expanding access to methadone treatment in Ohio through federally qualified health centers and a chain pharmacy: A geospatial modeling analysis.

Jan 28, 2021

In the United States, methadone provision for opioid use disorder (OUD) occurs at opioid treatment programs (OTPs). Ohio recently enacted a policy to expand methadone administration to Federally Quali...

Isotonitazene: Fatal intoxication in three cases involving this unreported novel psychoactive substance in Switzerland.

Jan 28, 2021

The paper describes the first three deaths reported in Europe involved in isotonitazene consumption, a potent benzimidazole derivate opioid consumed in the recreational drug scene. Isotonitazene powde...

Analyzing the Effects of Stimulant Abuse in Patients With Burns

Dec 25, 2020

Illicit drug use—including use of stimulants like methamphetamine, amphetamines, and cocaine—continues to be a growing problem throughout the United States. Research has shown that the misuse of i...

CME: Reducing Unnecessary Opioids After Total Hip Arthroplasty

Nov 20, 2020

This course discusses a study that tested the hypothesis that implementing a multidisciplinary, patient-specific discharge protocol for prescribing and tapering opioids after total hip arthroplasty wo...

The Impact of NSAID Allergies on Opioid Use Disorder in Back Pain

Nov 02, 2020

The opioid epidemic continues to be a serious public health problem in the United States, with opioid-related overdoses claiming the lives of more than 47,000 Americans annually. Higher opioid dosages...

A Closer Look at Patterns in Prescription Opioid Use & Misuse Among Cancer Survivors

Aug 28, 2020

Recent reports have shown that about one-third of cancer survivors experience cancer-related pain, and prescription rates for opioids are higher for these patients than the general population. The Ame...

The Impact of Hydromorphone & Infective Endocarditis

Aug 10, 2020

The rate of infective endocarditis (IE) in people who inject drugs (PWID) has been rapidly increasing in recent years, explains Michael Silverman, MD. Dr. Silverman and colleagues hypothesized that th...

Prescription Pain Medication Use Among Adults: Estimates & Trends

Jul 28, 2020

National guidelines note that nonpharmacologic and non-opioid-containing pharmacologic therapies are preferred for managing chronic pain whenever appropriate. “Since the early 2000s, there has been ...

ASCO: Gastric Cancer Patients Respond to Trastuzumab Deruxtecan

Jun 02, 2020

Overall survival also extended with conjugate treatment In a small, phase II trial, patients with advanced gastric cancer were far more likely to respond to conjugate therapy with trastuzumab deruxte...

How COVID-19 Has Impacted the Opioid Crisis

May 07, 2020

When it comes to rates of infection and addiction, both the coronavirus pandemic and the opioid epidemic disproportionately impact the poorest and most vulnerable members of society. As physicians, it...

Inhaled Cannabis for Headache & Migraine

Mar 23, 2020

Today, a substantial proportion of medical cannabis users report using cannabis to manage headache and migraine, claiming that it is effective. However, research on the effectiveness of cannabis for t...

A Novel Approach to Opioid Disposal

Jan 10, 2020

Current estimates suggest that 70-90% of opioids prescribed after surgery go unused, with most patients not disposing these medications that can become a common source of misuse and abuse, explains Ch...

FDA Approves Ubrelvy for Acute Migraine Treatment

Jan 08, 2020

Significantly more patients treated with Ubrelvy versus placebo achieved pain freedom two hours post-treatment TUESDAY, Dec. 24, 2019 (HealthDay News) -- Ubrelvy (ubrogepant) tablets have been ap...

Number of Children With Opioid Poisonings Increasing

Jan 07, 2020

Percentage of critical care admissions and suicidal intent increased in each era. MONDAY, Dec. 30, 2019 (HealthDay News) -- The severity of pediatric admissions for acute opioid ingestions, especia...

Overdose, Relapse After Buprenorphine Discontinuation High

Dec 27, 2019

The longer patients continue with buprenorphine treatment, the lower their risk of adverse outcomes.   THURSDAY, Dec. 26, 2019 (HealthDay News) -- Buprenorphine treatment may be needed ...