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Vaccines

Unvaccinated Parents, Caregivers Who Want Their Kids Immunized

Aug 17, 2022

Clinicians should ask pertinent questions to help identify unvaccinated parents and caregivers who are open to giving their children the COVID-19 vaccination. Vaccine hesitancy continues to be...

COVID-19 Vaccination Continues to Reduce Healthcare Burden

Aug 03, 2022

In just a month's time in late 2021, COVID-19 vaccination was estimated to prevent more than 50% of expected infections, hospitalizations, and deaths. Estimating the burden of COVID-19 prevented by...

A Practical Guide to Vaccination for Patients on Biologics

Jul 29, 2022

Biologic therapies may expose patients to an increased risk for contracting infections, including this from live-attenuated vaccines. Novel biologic therapies have become the preferred treatmen...

Missed Vaccination Opportunities for Invasive Pneumococcal Disease

May 25, 2022

Over half of patients with invasive pneumococcal disease (IPD) had a missed opportunity to be vaccinated within our healthcare system prior to developing IPD. Invasive pneumococcal disease (IPD...

inDEPTH: Who Are the Women With Breast Cancer Survival Rates Near 100%?

May 16, 2022

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inDEPTH: COVID-19 Pediatric Vaccine Hesitancy Among Racially Diverse Parents

Apr 12, 2022

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Association of COVID-19 Vaccination With Symptomatic SARS-CoV-2 Infection by Time Since Vaccination and Delta Variant Predominance

Mar 24, 2022

For a study, researchers sought to assess the relationships between symptomatic SARS-CoV-2 infection and the receipt of BNT162b2, mRNA-1273, and Ad26.COV2.S by day since vaccination before and after D...

Efficacy of immunization with a recombinant S. aureus vaccine formulated with liposomes and ODN-CpG against natural S. aureus intramammary infections in heifers and cows.

Feb 28, 2022

The aims of the present study were to evaluate the ability of a subunit vaccine composed of recombinant molecules of α-toxin, β-toxin, FnBPA and ClfA, formulated with cationic liposomes and CpG-ODN,...

Evaluation of the efficacy of polymeric antigen BLSOmp31 formulated in a new cage-like particle adjuvant (ISPA) administered by parenteral or mucosal routes against Brucella ovis in BALB/c mice.

Feb 14, 2022

Brucella ovis is an economically important cause of epididymitis in rams worldwide. Polymeric BLSOmp31 was previously identified as a protective immunogen against this pathogen. In this study, BLSOmp3...

Yeast cell wall upregulated cell-mediated immune responses to Newcastle disease virus vaccine.

Feb 07, 2022

A recent study has suggested that yeast cell wall product (YP) enhanced serum hemagglutination inhibition (HI) titers and intestinal sIgA responses in chickens immunized with Newcastle disease virus (...

The Impact of Flu Vaccination on Survival for Elderly Men With COPD

Jan 24, 2022

Previous studies have established that patients aged 65 and older with COPD are at elevated risk for influenza-associated complications, such as hospitalization, ICU admissions, and death. Guidelines ...

Link Between Allergy History & Post-COVID-19 Vaccination Allergic Reactions

Jan 20, 2022

In December 2020, the FDA granted emergency use authorization for mRNA COVID-19 vaccines from Pfizer-BioNTech and Moderna. However, within days of this authorization, there were several reports of sev...

Nucleic Acid Delivery from Granular Hydrogels.

Nov 08, 2021

Nucleic acid delivery has applications ranging from tissue engineering to vaccine development to infectious disease. Cationic polymer condensed nucleic acids have been used with surface coated porous ...

Zika virus infection in pregnant women and their children: A review.

Sep 13, 2021

Zika virus (ZIKV) is an arthropod-borne virus (arbovirus) transmitted primarily by Aedes mosquitoes. ZIKV can be transmitted to humans by non-vector borne mechanisms such as sexual intercourse, matern...

Identification of in vivo expressed proteins in live attenuated lipopolysaccharide mutant that mediates heterologous protection against Leptospira spp.

Sep 13, 2021

Leptospirosis vaccines that elicit broad protection against a range of pathogenic Leptospira spp. would overcome a major drawback of currently licensed bacterin vaccines. Live attenuated vaccine produ...

Evaluation of SARS-CoV-2 RT-PCR test results from a pandemic hospital according to demographic data.

Sep 06, 2021

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leading to coronavirus disease 2019 (COVID-19) in China at the end of 2019 has resulted in a global pandemic. On 11 March ...

Nanovaccine biomineralization for cancer immunotherapy: a NADPH oxidase-inspired strategy for improving antigen cross-presentation via lipid peroxidation.

Sep 06, 2021

Current efforts to develop novel vaccine nanotechnologies to increase cytotoxic T lymphocytes have met the challenges of the limited efficacy of antigen cross-presentation. Recent studies have uncover...

Plant-based vaccine research development against viral diseases with emphasis on Ebola virus disease: A review study.

Sep 06, 2021

Ebola virus infection results in the fast onset of severe acute haemorrhagic fever with high mortality. The Ebola virus is labelled as a category A pathogen. Vaccines against the Ebola virus (EBOV) ar...

TLR Ligand Loaded Exosome Mediated Immunotherapy of Established Mammary Tumor In Mice.

Aug 23, 2021

Tumor-derived exosomes (TEXs) could be harnessed as an immunotherapeutic cancer vaccine. These nanovesicles are inherently possesses rich tumor antigen reservoirs. Due to their undesirable features su...

Shell-mediated phagocytosis to reshape viral-vectored vaccine-induced immunity.

Aug 23, 2021

Adenovirus (Ad) has been extensively developed as a gene delivery vector, but the potential side effect caused by systematic immunization remains one major obstacle for its clinical application. Needl...