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ADHD/ADD

Functional MHCI deficiency induces ADHD-like symptoms with increased dopamine D1 receptor expression.

May 24, 2021

Inappropriate synaptic development has been proposed as a potential mechanism of neurodevelopmental disorders, including attention-deficit hyperactivity disorder (ADHD). Major histocompatibility compl...

Acute alcohol intoxication modulates the temporal dynamics of resting electroencephalography networks.

May 06, 2021

This study aimed to provide a currently missing link between general intoxication-induced changes in overall brain activity and the multiple cognitive control deficits typically observed during acute ...

Burden and coping strategies of parents of children with attention deficit/ hyperactivity disorder in Hong Kong: A qualitative study.

May 06, 2021

Attention deficit/hyperactivity disorder is a prevalent mental disorder among children worldwide. The parents of children with ADHD experience great burden. However, burden and coping styles of these ...

Effects of the PCSK9 Antibody Alirocumab on Coronary Atherosclerosis in Patients with Acute Myocardial Infarction: A Serial, Multivessel, Intravascular Ultrasound, Near-Infrared Spectroscopy and Optical Coherence Tomography Imaging Study Rationale and Design of the PACMAN-AMI trial.

May 06, 2021

The risk for cardiovascular adverse events after acute myocardial infarction (AMI) remains high despite potent medical treatment including low-density lipoprotein cholesterol (LDL-C) lowering with sta...

Application of TLD devices for radon and thoron PAEC measurements in air is the concept of "total PAEC" useful?

Apr 29, 2021

The calibration of monitors of radon decay products is a difficult task, and even more so in the case of monitors detecting the products of thoron decay. An important issue here is the lack of primary...

Evaluation of Promega PowerSeq™ Auto/Y systems prototype on an admixed sample of Rio de Janeiro, Brazil: Population data, sensitivity, stutter and mixture studies.

Apr 22, 2021

Forensic DNA typing typically relies on the length-based (LB) separation of PCR products containing short tandem repeat loci (STRs). Massively parallel sequencing (MPS) elucidates an additional level ...

Safety of surgical fertility preservation procedures in children prior to Hematopoietic Stem Cell Transplant.

Apr 19, 2021

Long-term survival following hematopoietic stem cell transplant (HSCT) in childhood continues to improve and patients are thus increasingly faced with the late effects of treatment. Infertility is ver...

Prediction of minimum postmortem submersion interval (PMSI) based on eukaryotic community succession on skeletal remains recovered from a lentic environment.

Apr 19, 2021

Although recent studies explored using microbial succession during decomposition to estimate the postmortem interval (PMI) and postmortem submersion interval (PMSI), there is currently no published re...

Citrate ligand-enhanced microscale zero-valent aluminum corrosion for carbon tetrachloride degradation with high electron utilization efficiency.

Apr 19, 2021

Carbon tetrachloride (CT) is highly toxic and recalcitrant in groundwater. In recent years, zero-valent aluminum (ZVAl) is highly reductive but limited by its surface passivation film. One of the effe...

Computational Modeling of Structural Synaptic Plasticity in Echo State Networks.

Mar 25, 2021

Most existing studies on computational modeling of neural plasticity have focused on synaptic plasticity. However, regulation of the internal weights in the reservoir based on synaptic plasticity ofte...

OLIGO-AIRO: a national survey on the role of radiation oncologist in the management of OLIGO-metastatic patients on the behalf of AIRO.

Mar 25, 2021

In the last years, several evidences demonstrated the role of stereotactic body radiotherapy (SBRT) in the oligometastatic disease and the possibility to increase survival in selected patients. In 202...

The mammalian Hedgehog pathway is modulated by ANP32 proteins.

Mar 25, 2021

Medulloblastoma (MB) is the most common malignant brain tumor in children. Transcriptional profiling has so far delineated four major MB subgroups of which one is driven by uncontrolled Hedgehog (Hh) ...

Effectiveness of a dance-physiotherapy combined intervention in Parkinson's disease: a randomized controlled pilot trial.

Mar 22, 2021

Physical therapies have been recommended as crucial components in Parkinson's disease (PD) rehabilitation.The study aims to examine the effectiveness of a new dance-physiotherapy combined intervention...

A Pilot Economic Evaluation of Computerized Cognitive Behavioral Therapy for Alcohol Use Disorder as an Addition and Alternative to Traditional Therapy.

Mar 18, 2021

Computer-based delivery of cognitive behavioral therapy (CBT) may be a less costly approach to increase dissemination and implementation of evidence-based treatments for alcohol use disorder (AUD). Ho...

Toward a Point-of-Need Bioluminescence-Based Immunoassay Utilizing a Complete Shelf-Stable Reagent.

Mar 18, 2021

Enzyme-linked immunosorbent assays (ELISAs) are used extensively for the detection and quantification of biomolecules in clinical diagnostics as well as in basic research. Although broadly used, the i...

Heart-focused breathing and perceptions of burden in Alzheimer's caregivers: An online randomized controlled pilot study.

Mar 01, 2021

Informal caregivers of patients with Alzheimer's disease (AD) often experience high stress and reduced wellbeing and quality of life. HeartMath's Heart Lock-In® technique has been shown to reduce str...

Structural determinants underlying the adduct lifetime in the LOV proteins of Pseudomonas putida.

Feb 25, 2021

The primary photochemistry is similar among the flavin-bound sensory domains of LOV (Light-oxygen-voltage) photoreceptors, where upon blue-light illumination a covalent adduct is formed on the microse...

Utilizing genome wide data to highlight the social behavioral pathways to health: The case of obesity and cardiovascular health among older adults.

Feb 25, 2021

We use genome-wide data from the 1992-2016 Health and Retirement Study (n = 12,090) to characterize obesity among older adults as genetically or socially oriented. To illustrate the significance of ...

Perampanel effectiveness and safety as early add-on treatment for focal-onset seizures: PEREAGAL study.

Feb 25, 2021

Perampanel (PER) is an effective adjunctive therapy for controlling focal-onset seizures (FOS), but few studies have examined its effects as an early add-on for the treatment of FOS in daily clinical ...

Proteomic analyses Identify Major Vault Protein as a Prognostic Biomarker for Fatal Prostate Cancer.

Feb 22, 2021

The demographic shift towards an older population will increase the number of prostate cancer cases. A challenge in the treatment of prostate cancer is to avoid undertreatment of patients at high risk...