Kava kava (Piper methysticum) is a medicinal plant containing kavalactones that exert potent sedative, analgesic and anti-stress effects. However, their pharmacological effects and molecular targets remain poorly understood. The...
Read MoreThe activation of resident microglia and infiltrated monocytes are known potent mediators of chronic neuroinflammation following traumatic brain injury (TBI). In this study, we use a mouse model of blast-induced TBI (bTBI) to...
Read MoreWithania somnifera(L.)Dunal, also known as Ashwaghanda” in Sanskrit and as”Indian Winter Cherry in english”is an important medicinal herb. It is widely used in Indian systems of medicine as an adaptogen, nerve...
Read MoreInsufficient sleep has been argued to result in deleterious changes to mood in adolescents and offers promise as a modifiable risk factor. A systematic review of the literature regarding sleep duration and mood in adolescents...
Read MoreN-methyl-d-aspartate receptor (NMDAR) antagonists, including ketamine and nitrous oxide, are currently intensely studied as rapid-acting antidepressant agents. Interestingly, both of these compounds are also drugs of abuse....
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Differences identified in depression severity, symptom burden, and depression care
Read More Devices may activate prematurely if the blue safety release is removed using sideways force
Read MoreBrain-derived neurotrophic factor (BDNF) is a growth factor that plays vital roles in the neuron survival, growth, and neuroplasticity. Alteration to BDNF expression is associated with major depressive disorder. However, the...
Read MoreNo one has assessed urodynamic studies (UDS) to determine those steps that elicit the greatest anxiety, distress, and pain in children. We sought to systematically evaluate a child’s UDS experience to mollify these...
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