Bipolar Disorder - Physician's Weekly - Page 19
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Bipolar Disorder

Delayed sleep timing and circadian rhythms in pregnancy and transdiagnostic symptoms associated with postpartum depression.

Feb 25, 2020

Later sleep timing, circadian preference, and circadian rhythm timing predict worse outcomes across multiple domains, including mood disorders, substance use, impulse control, and cognitive function. ...

Whole-exome sequencing of 81 individuals from 27 multiply affected bipolar disorder families.

Feb 25, 2020

Bipolar disorder (BD) is a highly heritable neuropsychiatric disease characterized by recurrent episodes of depression and mania. Research suggests that the cumulative impact of common alleles explain...

Body Mass Index Status across Different Psychiatric Disorders in a National Survey amongst Children and Adolescents: To Identify the Role of Gender.

Feb 25, 2020

Body mass index undergoes a substantial change in some psychiatric disorders. This study aimed to explore the status of body mass index (BMI) in different psychiatric disorders in a national survey a...

Demographic and Clinical Characteristics, Including Subsyndromal Symptoms Across Bipolar-Spectrum Disorders in Adolescents.

Feb 25, 2020

Bipolar disorder (BD) is a debilitating illness that often starts at an early age. Prevention of first and subsequent mood episodes, which are usually preceded by a period characterized by subthresho...

Differential effects of lithium isotopes in a ketamine-induced hyperactivity model of mania.

Feb 25, 2020

Sub-anesthetic doses of ketamine produce an increase in rodent ambulation that is attenuated by co-administration of naturally-occurring lithium (LiN), the drug most commonly employed in the treatment...

Hypomania/Mania by DSM-5 definition based on daily smartphone-based patient-reported assessments.

Feb 17, 2020

The DSM-5 has introduced elevated/irritable mood and increased activity/ energy as equal and necessary criterion A symptoms for a diagnosis of (hypo)mania. The impact of these changes is poorly elucid...

Outcomes in patients with and without capacity in electroconvulsive therapy.

Feb 17, 2020

Electroconvulsive therapy (ECT) is an effective treatment for severe mental illness but access is limited for patients lacking consent capacity. We aimed to compare the symptomatic, cognitive, quality...

Mixed episodes and suicide risk: A community sample of young adults.

Feb 17, 2020

Suicide is the second leading cause of death among young adults worldwide, and few studies have assessed the factors associated with suicidality in this specific population. Thus, the aim of this stud...

Association between affective temperaments and mood features in bipolar disorder II: The role of insomnia and chronobiological rhythms desynchronization.

Feb 17, 2020

Bipolar disorders are complex disorders involving the interaction of multiple factors. Affective temperaments, insomnia, and chronobiological rhythms desynchronization may all contribute to bipolar di...

Serum zonulin and claudin-5 levels in patients with bipolar disorder.

Feb 17, 2020

The etiology in bipolar disorder has not been fully understanding. There are limited data regarding the relationship between the permeability of intestinal and blood-brain barrier (BBB), and bipolar d...

Validity and characteristics of patient-evaluated adherence to medication via smartphones in patients with bipolar disorder: exploratory reanalyses on pooled data from the MONARCA I and II trials.

Feb 13, 2020

Non-adherence to medication is associated with increased risk of relapse in patients with bipolar disorder (BD).To (1) validate patient-evaluated adherence to medication measured via smartphones again...

Complex Combination Pharmacotherapy for Bipolar Disorder: Knowing When Less Is More or More Is Better.

Feb 13, 2020

Combination pharmacotherapy for bipolar disorder is commonplace and often reflects the severity and complexity of the illness and the comorbid conditions frequently associated with it. Across treatmen...

Opposing Changes in the Functional Architecture of Large-Scale Networks in Bipolar Mania and Depression.

Feb 13, 2020

Manic and depressive phases of bipolar disorder (BD) show opposite symptoms in psychomotor, thought, and affective dimensions. Neuronally, these may depend on distinct patterns of alterations in the f...

Case report: manic episode with psychotic symptoms induced by hyponatremia.

Feb 13, 2020

In the literature, several cases of an association between hyponatremia and psychotic symptoms have been reported. We present the case of a young Caucasian male presenting with rapid, incoherent spee...

LSD Overdoses: Three Case Reports.

Feb 13, 2020

In academic settings around the world, there is a resurgence of interest in using psychedelic substances for the treatment of addictions, posttraumatic stress disorder, depression, anxiety, and other ...

Sedentary Behavior, Activity Linked to Depression at Age 18

Feb 13, 2020

THURSDAY, Feb. 13, 2020 (HealthDay News) -- Sedentary behavior throughout adolescence is associated with the risk for depressive symptoms at age 18 years, according to a study published online Feb. 11...

Intrinsic brain activity of subcortical-cortical sensorimotor system and psychomotor alterations in schizophrenia and bipolar disorder: A preliminary study.

Feb 10, 2020

Alterations in psychomotor dimension cut across different psychiatric disorders, such as schizophrenia (SCZ) and bipolar disorder (BD). This preliminary study aimed to investigate the organization of ...

The treatment of acute agitation associated with psychosis or mania: investigational drugs in early clinical development, clinical context and potential place in therapy.

Feb 10, 2020

Acute agitation in patients with schizophrenia or bipolar disorder may require pharmacologic management before it progresses to aggressive behavior. Ideal medication characteristics for this indicatio...

The origin of our modern concept of mania in texts from 1780 to 1900.

Feb 10, 2020

The development of the modern concept of mania is explored by a review and analysis of 28 psychiatric texts in English, French, and German published in Western Europe and North America from 1780 to 19...

A closer look at the nosological status of the highs (hypomanic symptoms) in the postpartum period.

Feb 10, 2020

Studies from several countries have reported occurrence of the highs (hypomanic symptoms) immediately after childbirth; however, questions remain about the relationship of the highs with mood disorder...