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Bipolar Disorder

'Pediatric Bipolar Disorder' rates are still lower than claimed: a re-examination of eight epidemiological surveys used by an updated meta-analysis.

Jul 01, 2021

'Pediatric bipolar disorder' (PBD) is a controversial diagnosis with varying rates of clinical diagnosis. A highly cited meta-analysis (Van Meter et al. 2011) of a dozen epidemiological surveys sugges...

Early Life Stress and Chronobiological Rhythms Desynchronization: Possible Impact on Mood Symptoms and Suicidal Ideation in Bipolar Disorder.

Jul 01, 2021

The study aimed at investigating the potential impact of early stressful events on the clinical manifestations of bipolar disorder (BD). A sample of 162 adult individuals with BD was assessed using th...

Resilience in severe mental disorders: correlations to clinical measures and quality of life in hospitalized patients with major depression, bipolar disorder, and schizophrenia.

Jul 01, 2021

To evaluate resilience in severe mental disorders and correlate it with clinical measures and quality of life.Resilience (Resilience Scale, RS) and quality of life (WHOQOL-BREF questionnaire) were pro...

Residual symptoms in bipolar disorders: Findings from the bipolar Disorder course and outcome study from India (BiD-CoIN study).

Jun 24, 2021

To explore the prevalence of residual symptoms (both depressive and manic) and their correlates in subjects with bipolar disorder in clinical remission.This multicentric cross-sectional study included...

Trajectory of insight on various dimensions among bipolar disorder in-patients.

Jun 24, 2021

Insight is awareness of one's symptoms, illness, and need for treatment. In bipolar disorder, insight is better in bipolar depression and nonpsychotic depression when compared with mania and psychotic...

Using Screening Scales for Bipolar Disorder in Epidemiologic Studies: Lessons Not Yet Learned.

Jun 24, 2021

In a recent issue in the journal, Humpston, Bebbington, and Marwaha (2021) reported the results of the first large epidemiological study of bipolar disorder in England. The prevalence estimate of bipo...

Effects of Cariprazine on Cognition in Patients With Bipolar Mania or Mixed States: Post Hoc Analysis From 3 Randomized, Controlled Phase III Studies.

Jun 17, 2021

Cariprazine, a dopamine D3-preferring D3/D2 and serotonin 5-HT1A receptor partial agonist, is approved for the treatment of schizophrenia and for depressive, manic, or mixed episodes associated with b...

Ornithine Transcarbamylase Deficiency Presenting with Symptoms of Mania in a Young Adult Male.

Jun 17, 2021

The purpose of this case study is to review the clinical presentation and medical workup of a young adult male presenting with acute behavior changes in the setting of undiagnosed ornithine transcarba...

Trait sensation seeking is associated with heightened beta-band oscillatory dynamics over left ventrolateral prefrontal cortex during reward expectancy.

Jun 10, 2021

Sensation Seeking, the proclivity toward novel and stimulating experiences, is associated with greater left ventrolateral prefrontal cortex (vlPFC) activity during uncertain reward expectancy. Here, w...

ADHD and Bipolar Disorder in Adulthood: Clinical and Treatment Implications.

Jun 03, 2021

Attention deficit hyperactivity disorder (ADHD) is a condition that usually has its onset in childhood. Although the disorder persists into adulthood in half of cases, adult ADHD is often not recogniz...

Index Depressive Episode and Antidepressant Exposure Were Associated with Illness Characteristics of Pediatric Bipolar Disorder.

Jun 03, 2021

Pediatric bipolar disorder (PBD) is a serious, recurrent disorder leading to severe functional impairment. As a first mood episode, index episode could affect the long-term course of the illness. This...

Chronic lithium treatment alters the excitatory/ inhibitory balance of synaptic networks and reduces mGluR5-PKC signalling in mouse cortical neurons.

Jun 03, 2021

Bipolar disorder is characterized by cyclical alternation between mania and depression, often comorbid with psychosis and suicide. Compared with other medications, the mood stabilizer lithium is the m...

[Cognitive impairment in remitted patients with bipolar disorder].

May 31, 2021

To assess the frequency and severity of cognitive impairment as well as its correlations with clinical characteristics in remitted patients with bipolar disorder (BD).Eighty-five patients with BD type...

Development of the Thought Disorder Measure for the Hierarchical Taxonomy of Psychopathology.

May 31, 2021

The Hierarchical Taxonomy of Psychopathology consortium aims to develop a comprehensive self-report measure to assess psychopathology dimensionally. The current research describes the initial conceptu...

Longitudinal grey matter changes following first episode mania in bipolar I disorder: A systematic review.

May 31, 2021

While widespread grey matter (GM) changes are seen in bipolar I disorder (BD-I), it is unclear how early in the illness such changes emerge. To date there has been little synthesis of findings regardi...

Feasibility and Efficacy of Delivering Cognitive Behaviour Therapy through Online Psychotherapy Tool (OPTT) for Depression: Protocol.

May 17, 2021

Major Depressive Disorder (MDD) is a prevalent and debilitating mental health disorder. Among different therapeutic approaches (e.g., medication, psychotherapy), psychotherapy in the form of cognitive...

Hospital Presentation for Self-Harm in Youth as a Risk Marker for Later Psychotic and Bipolar Disorders: A Cohort Study of 59 476 Finns.

May 17, 2021

Expanding clinical strategies to identify high risk groups for psychotic and bipolar disorders is a research priority. Considering that individuals diagnosed with psychotic and bipolar disorder are at...

Therapeutic lithium alters polar head-group region of lipid bilayer and prevents lipid peroxidation in forebrain cortex of sleep-deprived rats.

May 17, 2021

Lithium is regarded as a unique therapeutic agent for the management of bipolar disorder (BD). In efforts to explain the favourable effects of lithium in BD, a wide range of mechanisms was suggested. ...

Assessment of Affective-Behavioral States in Parkinson's Disease Patients: Toward a New Screening Tool.

May 13, 2021

Assessment of affective-behavioral states in patients with Parkinson's disease (PD) undergoing deep brain stimulation (DBS) is essential.To analyze well-established questionnaires as a pilot-study wit...

Are publications on zoological taxonomy under attack?

May 13, 2021

Taxonomy is essential to biological sciences and the priority field in face of the biodiversity crisis. The industry of scientific publications has made extensive promotion and display of bibliometric...