Informal caregivers of patients with Alzheimer’s disease (AD) often experience high stress and reduced wellbeing and quality of life. HeartMath’s Heart Lock-In® technique has been shown to reduce stress. In a...
Neurofilament light chain (NFL) level in biofluids is a sensitive measure of axonal damage and a promising biomarker in neurodegenerative diseases. In Parkinson’s disease (PD), NFL can distinguish PD from other...
The pedunculopontine nucleus (PPN) undergoes significant anatomic and electrophysiological alterations in Parkinson’s disease (PD), severely impacting locomotion. However, the effect of 6-hydroxydopamine (6-OHDA) lesion...
Arsenic is a metalloid that has been hypothesized to be an enviromental risk factor for Alzheimer’s disease (AD), a disease having hyperphosphorylated tau aggregate as a marker. The present study demonstrated that...
The characterization of the distinct dynamic functional connectivity (dFC) patterns that activate in the brain during rest can help to understand the underlying time-varying network organization. The presence and behavior of...
The entorhinal-hippocampal system contains distinct networks subserving declarative memory. This system is selectively vulnerable to changes of ageing and pathological processes. The entorhinal cortex (EC) is a pivotal component...
Parkinson’s disease (PD) and Dementia with Lewy Bodies (DLB) prognosis depends on cognitive function evolution. Sleep disorders, as objectivated by polysomnography (PSG), are intimately connected with PD and DLB...
Recent studies have confirmed that white matter hyperintensities (WMHs) accumulated in strategic brain regions can predict cognitive impairments associated with Alzheimer’s disease (AD). The knowledge of white matter...
Emerging evidence suggests that the gut microbiota plays an important role in the pathological progression of Alzheimer’s disease (AD). Photobiomodulation (PBM) therapy is believed to have a positive regulatory effect on...
Heparan sulfate (HS) can play important roles in the biology and pathology of amyloid β (Aβ), a hallmark of Alzheimer’s disease. To better understand the structure-activity relationship of HS/Aβ interactions, synthetic HS...
Late-life depression (LLD) is associated with an increased risk of all-cause dementia and may involve Alzheimer’s disease pathology. Twenty-one LLD patients who met the Diagnostic and Statistical Manual of Mental...
The mini-Addenbrooke’s Cognitive Examination (m-ACE) is a brief cognitive battery that assesses 5 subdomains of cognition (attention, memory, verbal fluency, visuospatial abilities, and memory recall). It is scored out of...
