Dementia

Parkinson’s disease (PD) is a neurodegenerative disease and is characterized by resting tremor, dementia, and gait disorder. Previous studies have indicated that long noncoding RNA (lncRNA) participates in the regulation...

This study assessed factors associated with disability and life satisfaction in a large cohort of 2246 Australian adults with neurological disorders who completed an online survey of mental health and wellbeing. It was...

Some patients with Parkinson’s disease (PD) undergoing levodopa‒carbidopa intestinal gel (LCIG) treatment experience motor fluctuations in the afternoon. The migrating motor complex, a specific periodic migrating...

Carriers of the G2019S mutation of LRRK2 provide a great opportunity to investigate the premotor stages of PD. We have studied by serial clinical and DaT-SPECT evaluations a cohort of asymptomatic carriers of LRRK2-G2019S...

Of all types of dementia, Alzheimer’s disease is the type that has the highest proportion of cases and is the cause of substantial medical and economic burden. The mechanism of Alzheimer’s disease is closely...

In this era of technology, neurological disorders are the most prevalent disorders in growing population. Alzheimer’s and Parkinson’s diseases are the most common neurological disorders which are manifested by any...

Studies of the metal content of metalloproteins in tissues from the human central nervous system (CNS) can be compromised by preparative techniques which alter levels of, or interactions between, metals and the protein of...

Impaired olfaction and reduced cholinergic nucleus 4 (Ch4) volume both predict greater cognitive decline in Parkinson’s disease (PD). We examined the relationship between olfaction, longitudinal change in cholinergic basal...

Parkinson’s disease (PD) patients may be at increased risk of Covid-19 mortality due to the nature of their disease or underlying conditions.The information of 12,909 Covid-19 patients who were hospitalized during the last...

There is emerging evidence that analysing the entropy and complexity of biomedical signals can detect underlying changes in physiology which may be reflective of disease pathology. This approach can be used even when only short...

Physical exercise is an important component of managing Alzheimer’s disease (AD). miRNAs can be modulated by exercise intervention.The study explored the involvement and potential mechanism of miR-192-5p in the protective...