Dementia
May 20, 2022
1. Physical activity was significantly associated with a decreased incidence of all-cause dementia and Alzheimer’s disease, irrespective of follow-up length, baseline age and study quality. 2...
Apr 12, 2022
Patients with HF who developed delirium were more likely to die within 30 days post-hospitalization and within a year post-hospitalization. Dementia and delirium are highly prevalent conditions...
Feb 02, 2022
Adverse childhood experiences (ACEs) are associated with a greater risk for many common conditions that contribute to mortality in adulthood, but limited evidence examines whether ACEs correlate with ...
Oct 25, 2021
According to epidemiological studies, Parkinson's disease (PD) patients with probable REM sleep behavior disorder (pRBD) are more prone to develop impulse control disorders (ICDs), which is shown to b...
Sep 13, 2021
Parkinson's disease (PD) is a neurodegenerative disease and is characterized by resting tremor, dementia, and gait disorder. Previous studies have indicated that long noncoding RNA (lncRNA) participat...
Sep 13, 2021
This study assessed factors associated with disability and life satisfaction in a large cohort of 2246 Australian adults with neurological disorders who completed an online survey of mental health and...
Sep 13, 2021
Some patients with Parkinson's disease (PD) undergoing levodopa‒carbidopa intestinal gel (LCIG) treatment experience motor fluctuations in the afternoon. The migrating motor complex, a specific peri...
Aug 19, 2021
Carriers of the G2019S mutation of LRRK2 provide a great opportunity to investigate the premotor stages of PD. We have studied by serial clinical and DaT-SPECT evaluations a cohort of asymptomatic car...
Aug 19, 2021
Of all types of dementia, Alzheimer's disease is the type that has the highest proportion of cases and is the cause of substantial medical and economic burden. The mechanism of Alzheimer's disease is ...
Aug 05, 2021
In this era of technology, neurological disorders are the most prevalent disorders in growing population. Alzheimer's and Parkinson's diseases are the most common neurological disorders which are mani...
Aug 05, 2021
Studies of the metal content of metalloproteins in tissues from the human central nervous system (CNS) can be compromised by preparative techniques which alter levels of, or interactions between, meta...
Aug 05, 2021
Impaired olfaction and reduced cholinergic nucleus 4 (Ch4) volume both predict greater cognitive decline in Parkinson's disease (PD). We examined the relationship between olfaction, longitudinal chang...
Jul 15, 2021
Parkinson's disease (PD) patients may be at increased risk of Covid-19 mortality due to the nature of their disease or underlying conditions.The information of 12,909 Covid-19 patients who were hospit...
Jul 15, 2021
There is emerging evidence that analysing the entropy and complexity of biomedical signals can detect underlying changes in physiology which may be reflective of disease pathology. This approach can b...
Jul 15, 2021
Physical exercise is an important component of managing Alzheimer's disease (AD). miRNAs can be modulated by exercise intervention.The study explored the involvement and potential mechanism of miR-192...
Jul 12, 2021
The latest installment of the #PWChat series centered around trends in continuing medical education. Below are the highlights from the chat. You can read the full transcript here, by scrolling th...
Jun 24, 2021
Fibril formation and aggregation of α-synuclein are important for the pathogenesis of neurodegenerative disorders including Parkinson's disease. In familial Parkinson's disease, the G51D mutation of ...
Jun 24, 2021
Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases, characterized by the accumulation of abnormal tau proteins within neurons and amyloid plaques in the brain parenchyma,...
Jun 24, 2021
Among persons with amnestic mild cognitive impairment (aMCI), intrusion errors on subscales that measure proactive semantic interference (PSI) may be among the earliest behavioral markers of elevated ...
Jun 10, 2021
The structural dynamics of the amyloid protein aggregation process are associated with neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. High-speed atomic force micros...