Dementia

Alzheimer’s disease (AD) is the most common neurodegenerative disease. AD has become an important social health problem but there are few therapeutic drugs. Many researchers devote to the development of drugs for the...

Formation of amyloid plaques is the hallmark of Alzheimer’s disease. Our early studies show that lead (Pb) exposure in PDAPP transgenic mice increases β-amyloid (Aβ) levels in the cerebrospinal fluid (CSF) and hippocampus,...

Ferrous sulfate (FeSO)-directed dual-cross-linked hydrogels were designed for application in single-syringe injections. The use of FeSO, rather than other iron salts, can modulate the gelation time and make it available for...

Alzheimer’s disease (AD) is the leading cause of dementia, accounting for 70% of cases worldwide. By 2050, dementia prevalence will have tripled, with most new cases occurring in low- and middle-income countries. Mild...

In the context of the public health burden posed by increases in Alzheimer’s Disease (AD) prevalence around the globe and the related research efforts to identify modifiable risk factors for the disease, we sought to...

With high numbers of persons with dementia living in residential care, it is vital to maximize psychosocial well-being for this population, in this setting. The current study observed whether proportions of positive affect in...

The α-synuclein (αSN) amyloid fibrillization process is known to be a crucial phenomenon associated with neuronal loss in various neurodegenerative diseases, most famously Parkinson’s disease. The process involves...