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Psychiatry General

The role of the gut microbiome in weight-gain in schizophrenia patients treated with atypical antipsychotics: Evidence based on altered composition and function in a cross-sectional study.

Sep 18, 2023

We aimed to explore the interconnection between the weight-gain in schizophrenia patients with atypical antipsychotic treatment and gut microbiome.This study employed a cross-sectional design, encompa...

Structural Degeneration of the Nucleus basalis of Meynert in Mild Cognitive Impairment and Alzheimer's Disease - Evidence from an MRI-based Meta-Analysis.

Sep 18, 2023

Recent models of Alzheimer's Disease (AD) suggest that neuropathological changes of the medial temporal lobe, especially entorhinal cortex, are preceded by degenerations of the cholinergic Nucleus bas...

Low and very low lithium levels: Thyroid effects are small but still require monitoring.

Sep 18, 2023

Low doses of lithium, as might be used for mood or dementia prevention, do not carry the same renal, toxicity, and tolerability problems of doses used for prophylaxis or treatment of mania. However, t...

Bipolar At-Risk Criteria and Risk of Bipolar Disorder Over 10 or More Years.

Sep 18, 2023

Predicting the onset of bipolar disorder (BD) could facilitate preventive treatments. Among risk measures, bipolar at-risk (BAR) criteria have shown promise in predicting onset of bipolar disorder in ...

Forensic psychiatry patients, services, and legislation in Nunavut and Greenland.

Sep 11, 2023

Circumpolar regions face unique challenges in establishing and maintaining mental health care systems, including forensic psychiatry services. The scarcity of data and lack of evidence concerning the ...

Pretrauma risk factors and posttraumatic stress disorder symptoms following subsequent exposure: Multilevel and univariate meta-analytical approaches.

Sep 11, 2023

The endeavour to comprehend why certain individuals develop posttraumatic stress disorder (PTSD) symptoms subsequent to experiencing traumatic events, while others do not, underscores the paramount im...

Meta-analysis of the effects of adjuvant drugs in co-occurring bipolar and substance use disorder.

Sep 11, 2023

Individuals with bipolar disorder (BD) often have co-occurring substance use disorders (SUDs), which substantially impoverish the course of illness. Despite the importance of this dual diagnosis, the ...

Effect of ginger root powder on gastrointestinal bacteria composition, gastrointestinal symptoms, mental health, fatigue, and quality of life: A double-blind placebo-controlled trial.

Sep 11, 2023

Despite compositional alterations in gastrointestinal microbiota being purported to underpin some of the therapeutic effects of ginger, the effect of a standardized ginger supplement on gut microbiota...

The burden of major depressive disorder in the Middle East and North Africa region, 1990-2019.

Sep 11, 2023

Major depressive disorder (MDD) is one of the leading causes of disability. We aimed to report the MDD attributable prevalence, incidence and years lived with disability (YLDs) in the Middle East and ...

Effects of institutional rearing and foster care intervention on error monitoring and externalizing behaviors in adolescence.

Sep 11, 2023

Children raised in institutions display deficits in error monitoring and increased psychopathology. Deficits in error monitoring might be a pathway for the emergence of psychopathology in previously i...

Impact of a pre-test measurement of alcohol craving in cue-exposure studies: relationship with social desirability and demand effects.

Sep 04, 2023

Craving is one of the most studied concepts in the field of addiction. It is often investigated with repeated measure experimental designs using self-reported scales. However, the explicit nature of s...

Hydralazine inhibits neuroinflammation and oxidative stress in APP/PS1 mice via TLR4/NF-κB and Nrf2 pathways.

Sep 04, 2023

Alzheimer's disease (AD) is a common chronic progressive neurodegenerative disorder, and curative treatment has not been developed. The objective of this study was to investigate the potential effects...

[Features of the neurocognitive profile of patients with protracted and chronic endogenous manic and manic-delusional states].

Sep 04, 2023

To study the neurocognitive profile of patients with protracted and chronic endogenous manic and manic-delusional states (EMDS).Thirty-two female patients, aged 18 to 55 years (mean age 36.2±10.2 yea...

Cardiovascular variations in patients with major depressive disorder versus bipolar disorder.

Sep 04, 2023

Differentiating depression in major depressive disorder and bipolar disorder is challenging in clinical practice. Therefore, reliable biomarkers are urgently needed to differentiate between these dise...

Shared and specific neurobiology in bipolar disorder and unipolar disorder: Evidence based on the connectome gradient and a transcriptome-connectome association study.

Sep 04, 2023

Distinguishing bipolar disorder (BD) and unipolar disorder (UD) remains challenging. To identify the common and diagnosis-specific neuropathological alterations and their potential molecular mechanism...

Guideline No. 441: Antenatal Fetal Health Surveillance.

Sep 04, 2023

To summarize the current evidence and to make recommendations for antenatal fetal health surveillance (FHS) to detect perinatal risk factors and potential fetal decompensation in the antenatal period ...

The prevalence of non-affective psychosis in refugee populations: A systematic review.

Aug 28, 2023

As we face the largest refugee crisis since World War Two, research is increasingly examining the impact of forced displacement. The risk of non-affective psychosis in refugees is evidenced to be sign...

NIRS-aided differential diagnosis among patients with major depressive disorder, bipolar disorder, and schizophrenia.

Aug 28, 2023

To establish a clinically applicable neuroimaging-guided diagnostic support system that uses near-infrared spectroscopy (NIRS) for differential diagnosis at the individual level among major depressive...

An in-depth association analysis of genetic variants within nicotine-related loci: Meeting in middle of GWAS and genetic fine-mapping.

Aug 28, 2023

In the last two decades of Genome-wide association studies (GWAS), nicotine-dependence-related genetic loci (e.g., nicotinic acetylcholine receptor - nAChR subunit genes) are among the most replicable...

Brain-wide genome-wide colocalization study for integrating genetics, transcriptomics and brain morphometry in Alzheimer's disease.

Aug 28, 2023

Alzheimer's disease (AD) is one of the most common neurodegenerative diseases. However, the AD mechanism has not yet been fully elucidated to date, hindering the development of effective therapies. In...

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