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Opioids

Preliminary psychometric evaluation of the patient reported experience measure for addiction treatment (PREMAT).

Aug 05, 2021

Patient-reported experience measures (PREMs) are recommended for use in evaluating person-centred care. To date, a PREM has not been validated for residential alcohol and other drug (AOD) treatment. U...

Excessive and pathological Internet use - Risk-behavior or psychopathology?

Aug 02, 2021

Pathological Internet use (but only with respect to gaming) is classified as mental disorder in the ICD-11. However, there is a large group of adolescents showing excessive Internet use, which may rat...

Targeting diacylglycerol lipase reduces alcohol consumption in preclinical models.

Jul 26, 2021

Alcohol use disorder (AUD) is associated with substantial morbidity, mortality, and societal cost, and pharmacological treatment options for AUD are limited. The endogenous cannabinoid (eCB) signaling...

Unilateral rhomboid intercostal and subserratus plane block application for analgesia after laparoscopic cholecystectomy surgery :a quasi-experimental study.

Jul 22, 2021

Interfascial plane block applications can be used for postoperative pain after laparoscopic surgery. We aimed to investigate the effect of ultrasound-guided unilateral rhomboid intercostal and subserr...

Effects of transcranial direct current stimulation on experimental pain perception: A systematic review and meta-analysis.

Jul 22, 2021

Many studies have examined the effectiveness of transcranial direct current stimulation (tDCS) on human pain perception in both healthy populations and pain patients. Nevertheless, studies have yielde...

Chronic High-Risk Prescription Opioid Use in Patients With HIV

Jul 20, 2021

A study has found that opioid prescriptions, including receipt of prescriptions for long durations, appear to be common among people living with HIV who are in primary care. Efforts are needed to prev...

Healthcare professionals' experiences of the barriers and facilitators to paediatric pain management in the community at end-of-life: A qualitative interview study.

Jul 19, 2021

Inadequate pain management in community paediatric palliative care is common. Evidence to inform improved pain management in this population is limited.To explore the barriers and facilitators to paed...

Co-exposure of cocaine and cannabinoids and its association with select biological, behavioural and health outcomes: A systematic scoping review of multi-disciplinary studies.

Jul 19, 2021

Cocaine use entails severe health- and social-related harms globally. Treatment options for cocaine dependence are highly limited. Benefits of cannabinoids for addiction have been documented, making i...

Intervertebral foramen injection of plerixafor attenuates neuropathic pain after chronic compression of the dorsal root ganglion: Possible involvement of the down-regulation of Nav1.8 and Nav1.9.

Jul 15, 2021

Neuropathic pain is a common chronic pain condition with major impact on quality of life. However, its physiopathologic mechanism remains unknown and pain management is still a challenge. Accumulating...

Transdermal delivery of flurbiprofen from polyoxypropylene-polyoxyethylene block copolymer stabilized reduced graphene oxide to manage pain in spondylitis: In vitro and in vivo studies.

Jul 15, 2021

Ankylosing spondylitis is an inflammatory arthritic disease affecting the spine and large joints, causing severe pain. Flurbiprofen is widely used as an oral formulation (tablet dosage form) to contro...

Prevalence and predictors of the persistence and incidence of adolescent internet addiction in Mainland China: A two-year longitudinal study.

Jul 15, 2021

Internet addiction (IA), which can have different development patterns, is considered a serious problem among adolescents. Due to the increasing number of adolescent internet users in Mainland China, ...

Phytochemical analysis and biological activities of "Cherchoomoro" (Nepeta adenophyta Hedge).

Jul 12, 2021

Nepeta adenophyta Hedge (Lamiaceae) is an endemic therapeutic herb from Astore, Gilgit. This plant species has been reported among the local communities, especially for treating abdominal pain, kidney...

A systematic review of stigma interventions for providers who treat patients with substance use disorders.

Jul 05, 2021

Stigma surrounding substance use disorders (SUDs) is a frequently cited barrier to treatment engagement. Research consistently demonstrates that healthcare professionals' attitudes towards patients wi...

CME/CE: Assessing Prescription Opioid Medical Use & Misuse in Parents & Offspring

Jul 02, 2021

This course discusses a study that examined associations between parental and adolescent prescription opioid medical use and misuse....

Examining Characteristics Linked With Poor Outcomes in Opioid Prescribing

Jun 30, 2021

“In recent decades, the medical community has become acutely aware of the dangers posed by prescription opioids and their contribution to the opioid epidemic,” explains David R. Foster, PharmD, FC...

Nanoparticle-Cartilage Interaction: Pathology-Based Intra-articular Drug Delivery for Osteoarthritis Therapy.

Jun 24, 2021

Osteoarthritis is the most prevalent chronic and debilitating joint disease, resulting in huge medical and socioeconomic burdens. Intra-articular administration of agents is clinically used for pain m...

Korean validation of the Motives for Online Gaming Questionnaire: Focusing on its factor structure and incremental validity.

Jun 24, 2021

Research has suggested that considering gaming motives can be useful in differentiating between heterogenous online game users. This study validated the Korean version of the Motives for Online Gaming...

Glutamine addiction in virus-infected mammalian cells: A target of the innate immune system?

Jun 17, 2021

Control of core cell metabolism is a key aspect of the evolutionary conflict between viruses and the host's defence mechanisms. From their side, the invading viruses press the accelerator on their hos...

Social media use in China before and during COVID-19: Preliminary results from an online retrospective survey.

Jun 07, 2021

More people reported symptoms of stress, anxiety and depression during the outbreak of the coronavirus (COVID-19). They might have increased their social media use during the outbreak of COVID-19 comp...

The influence of perceived parental phubbing on adolescents' problematic smartphone use: A two-wave multiple mediation model.

Jun 07, 2021

Using a two-wave longitudinal design, the current study examined the relationship between early perceived parental phubbing and subsequent problematic smartphone use. As loneliness is a sensitive indi...