Pain Management | Physician's Weekly
Advertisement

Pain Management

Chest Pain

Oct 06, 2021

"I have this stabbing chest pain." ...

"I Know It Is Going to Ruin Their Life:" Fortune-Telling, Agency, and Harm Reduction in Narratives Concerning Injection Initiation Assistance.

Aug 05, 2021

Considering most people who inject drugs (PWID) received help with the first injection, understanding the perspective of potential 'initiators' is a priority to inform harm reduction interventions. Th...

Recommendations for Dosing & Administering Medical Cannabis for Chronic Pain

Jul 31, 2021

Despite a need for more robust evidence, many patients with chronic pain are being treated with medical cannabis and cannabinoids. In the Journal of Cannabis Research, the Global Task Force on Dosing ...

Chronic High-Risk Prescription Opioid Use in Patients With HIV

Jul 20, 2021

A study has found that opioid prescriptions, including receipt of prescriptions for long durations, appear to be common among people living with HIV who are in primary care. Efforts are needed to prev...

Examining Why Patients With Chronic Hepatitis C Drink Alcohol

Jun 23, 2021

The burden of chronic liver disease in the United States is substantial, affecting about 4.5 million American adults, according to recent data. The end result of chronic liver disease is cirrhosis, wh...

CDC's Efforts to Quantify Prescription Opioid Overdose Deaths Fall Short.

Mar 25, 2021

In a 2018 report titled, Quantifying the Epidemic of Prescription Opioid Overdose Deaths, four senior analysts of the Centers for Disease Control and Prevention (CDC), including the head of the Epidem...

Assessing Prescription Opioid Medical Use & Misuse in Parents & Offspring

Mar 22, 2021

According to recent data, nearly 50% of adolescents who misuse prescription opioids report obtaining the drugs from relatives or friends. Understanding the parental origins of adolescent prescription ...

Factor structure and psychometric properties of the Connor-Davidson resilience scale (CD-RISC) in individuals with opioid use disorder.

Feb 25, 2021

Resilience is defined as the capacity for an individual to maintain normal functioning and resist the development of psychiatric disorders in response to stress and trauma. Although previous investiga...

Comparison of psychological symptoms and cognitive functions in patients under maintenance treatment with methadone or buprenorphine, current opioid users and healthy subjects.

Feb 25, 2021

Methadone and buprenorphine can affect the psychological symptoms and cognitive functioning of substance users. This study aimed to compare psychological symptoms and neuropsychological functioning in...

Opioid Mortality Following Implementation of Medical Cannabis Programs in the United States.

Feb 25, 2021

The United States is in the midst of an opioid overdose epidemic. Emerging evidence suggests that medical cannabis (MC) may reduce use of opioids for pain in some individuals, with potential impacts o...

Inhibition of cAMP-phosphodiesterase 4 (PDE4) potentiates the anesthetic effects of Isoflurane in mice.

Feb 22, 2021

Despite major advances, there remains a need for novel anesthetic drugs or drug combinations with improved efficacy and safety profiles. Here, we show that inhibition of cAMP-phosphodiesterase 4 (PDE4...

Effect of suvorexant on morphine tolerance and dependence in mice: Role of NMDA, AMPA, ERK and CREB proteins.

Feb 22, 2021

The major problems of morphine use in the clinic are its tolerance and dependence. This study aimed to investigate the effect of suvorexant, a dual orexin receptor antagonist, on morphine-induced depe...

Evaluation of an emergency department-based opioid overdose survivor intervention: Difference-in-difference analysis of electronic health record data to assess key outcomes.

Feb 22, 2021

In recent years, a number of emergency department (ED)-based interventions have been developed to provide supports and/or treatment linkage for people who use opioids. However, there is limited resear...

Risk Factors Associated With Transition From Acute to Chronic Low Back Pain in US Patients Seeking Primary Care.

Feb 18, 2021

Acute low back pain (LBP) is highly prevalent, with a presumed favorable prognosis; however, once chronic, LBP becomes a disabling and expensive condition. Acute to chronic LBP transition rates vary w...

Enriched environment and social isolation differentially modulate addiction-related behaviors in male offspring of morphine-addicted dams: the possible role of μ-opioid receptors and ΔFosB in the brain reward pathway.

Feb 18, 2021

Prenatal opioids exposure negatively affects the neurobehavioral abilities of children born from dependence dams. Adolescent housing conditions can buffer the detrimental impacts of early life experie...

Intermittent REM sleep deprivation attenuates the development of morphine tolerance and dependence in male rats.

Feb 18, 2021

Opioid agonists are used in clinic for pain management, however this application is challenged by development of tolerance and dependence following prolonged exposure. Various approaches have been sug...

Tranexamic Acid Has No Effect on Post-operative Hemarthrosis or Pain Control Following ACL Reconstruction Using Bone Patella Tendon Bone Autograft: A Double-Blinded Randomized Control Trial.

Feb 04, 2021

The purpose of this double-blinded randomized controlled trial was to evaluate the use of intravenous (IV) tranexamic acid (TXA) in patients undergoing primary bone-patella tendon-bone (BTB) ACLR with...

A Clinical Trial of a Video Intervention Targeting Opioid Disposal After General Surgery: A Feasibility Study.

Feb 04, 2021

The opioid epidemic continues and although some initiatives have shown promise in reducing the number of opiates prescribed, few studies have focused on education of general surgery patients about hom...

Isotonitazene: Fatal intoxication in three cases involving this unreported novel psychoactive substance in Switzerland.

Jan 28, 2021

The paper describes the first three deaths reported in Europe involved in isotonitazene consumption, a potent benzimidazole derivate opioid consumed in the recreational drug scene. Isotonitazene powde...

Anxiety, Depression, & Chronic Pancreatitis

Jan 20, 2021

Psychiatric comorbidities are prevalent in patients with chronic pancreatitis (CP) and associated with pain and reduced quality of life (QOL), Anna Evans Phillips, MD, MS, explains. “Prior studies h...