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Sleep Disorders

PCSK9 Inhibitors and Neurocognitive Adverse Drug Reactions: Analysis of Individual Case Safety Reports from the Eudravigilance Database.

Dec 24, 2020

Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9Is) were associated with a risk of neurocognitive adverse drug reactions (ADRs).We aimed to investigate the occurrence of neuropsychiatri...

Common risk factors and therapeutic targets in obstructive sleep apnea and osteoarthritis: an unexpectable link?

Dec 24, 2020

Osteoarthritis (OA) and Obstructive Sleep Apnea (OSA) are two highly prevalent chronic diseases for which effective therapies are urgently needed. Recent epidemiologic studies, although scarce, sugges...

Comparative Evaluation of One-handed Versus Two-handed Mask Holding Techniques in Children During Inhalational Induction of Anesthesia: A Randomized Crossover Study.

Dec 21, 2020

We aimed to evaluate if two-handed mask airway is superior to one-handedmask airway during inhalational induction of anesthesiain children.A randomized, two period, crossover study was performed on 60...

Feasibility of an online cognitive behavioral therapy program to improve insomnia, mood, and quality of life in bereaved adults ages 55 and older.

Dec 21, 2020

The aim of the current study was to assess the feasibility and preliminary efficacy of utilizing an online Cognitive Behavioral Therapy for Insomnia (CBT-I) program in bereaved older adults (ages 55 a...

Prevalence of psychological disorders in the COVID-19 epidemic in China: A real world cross-sectional study.

Dec 21, 2020

This study aimed to explore the prevalence of psychological disorders and associated factors at different stages of the COVID-19 epidemic in China.The mental health status of respondents was assessed ...

Mental health outcomes among patients from Fangcang shelter hospitals exposed to COVID-19: An observational cross-sectional study.

Dec 17, 2020

The coronavirus disease 2019 (COVID-19) is not only attacking our physical health, but it is also increasing psychological suffering. This study aimed to observe the impact of the COVID-19 pandemic on...

The effect of acute morphine on sleep in male patients suffering from sleep apnea: Is there a genetic effect? An RCT Study.

Dec 17, 2020

Questionnaire-based studies have suggested genetic differences in sleep symptoms in chronic opioid users. The present study aims to investigate if there is a genetic effect on sleep architecture and q...

Polymeric Nanoencapsulation of Zaleplon into PLGA Nanoparticles for Enhanced Pharmacokinetics and Pharmacological Activity.

Dec 17, 2020

Zaleplon (ZP) is a sedative and hypnotic drug used for the treatment of insomnia. Despite its potent anticonvulsant activity, ZP is not commonly used for the treatment of convulsion since ZP is charac...

Greater Severity and Functional Impact of Post-traumatic Headache in Veterans With Comorbid Neck Pain Following Traumatic Brain Injury.

Dec 14, 2020

Post-traumatic headache (PTH) is a commonly experienced symptom after mild traumatic brain injury (mTBI). Blast injury- or blunt injury-related mechanisms for mTBI in veterans can also affect musculos...

Parent-Reported Symptoms and Medications Used Among Children With Severe Neurological Impairment.

Dec 14, 2020

Children with severe neurological impairment (SNI) often take multiple medications to treat problematic symptoms. However, for children who cannot self-report symptoms, no system exists to assess mult...

Occurrence of workplace violence and the psychological consequences of it among nurses working in psychiatric outpatient settings.

Dec 14, 2020

There is a scarcity of studies concerning violence and its consequences in psychiatric outpatient setting. This study aimed to explore the occurrence of workplace violence and the psychological conseq...

Dysregulation of the orexin/hypocretin system is not limited to narcolepsy but has far-reaching implications for neurological disorders.

Dec 10, 2020

Neuropeptides orexin A and B (OX-A/B, also called hypocretin 1 and 2) are released selectively by a population of neurons which projects widely into the entire central nervous system but are localized...

The Bidirectional Association Between Psoriasis & OSA

Dec 08, 2020

With psoriasis and obstructive sleep apnea (OSA) sharing various comorbidities and having a common pathogenesis of inflammatory and immune imbalance, many studies have examined the association between...

Rotigotine: A Review of Analytical Methods for the Raw Material, Pharmaceutical Formulations, and Its Impurities.

Dec 07, 2020

Rotigotine is a dopaminergic agonist developed for the treatment of Parkinson's disease and restless leg syndrome. The pure levorotatory enantiomer is marketed in several countries as a transdermal pa...

The Relationship between Simple Snoring and Sleep Bruxism: A Polysomnographic Study.

Dec 07, 2020

Simple snoring is defined as the production of sound in the upper aerodigestive tract during sleep, not accompanied by other pathologies. Sleep bruxism (SB) refers to repetitive phasic, tonic, or mixe...

Self-Isolation Due to COVID-19 Is Linked to Small One-Year Changes in Depression, Sleepiness, and Insomnia: Results from a Clinic for Sleep Disorders in Shiga Prefecture, Japan.

Dec 07, 2020

We aimed to analyze (a) the changes in depression, sleepiness, insomnia, and sleep habits in relation to the degree of self-isolation and (b) the effects of changes in sleep habits and social interact...

Internal Consistency and Convergent Validity of the Inventory of Hyperacusis Symptoms.

Dec 03, 2020

The aim was to assess the internal consistency and convergent and discriminant validity of a new questionnaire for hyperacusis, the Inventory of Hyperacusis Symptoms (IHS; Greenberg & Carlos 2018)...

Current state of hypnotic use disorders: Results of a survey using the Japanese version of Benzodiazepine Dependence Self-Report Questionnaire.

Dec 03, 2020

Benzodiazepine receptor agonists (BZ-RAs) are frequently prescribed to treat insomnia; however, their long-term use is not recommended. To introduce an appropriate pharmaco-therapy, the current state ...

Treatment of Obstructive Sleep Apnea-Hypopnea Syndrome With a Mandible Advanced Device Increases Nitric Oxide Release and Ameliorates Pulmonary Hypertension in Rabbits.

Dec 03, 2020

To investigate the effects of mandible advanced device (MAD) therapy for obstructive sleep apnea-hypopnea syndrome (OSAHS) on nitric oxide (NO) release and changes in pulmonary artery pressure and str...

Results of coblation midline glossectomy for obstructive sleep apnea.

Nov 30, 2020

The aim of this study is to determine the effectiveness of coblation midline glossectomy for obstructive sleep apnea (OSA) when used as an isolated procedure. We also aim to compare the effect of this...

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