Effect of IL-7 Therapy on Phospho-Ribosomal Protein S6 and TRAF1 Expression in HIV-Specific CD8 T Cells in Patients Receiving Antiretroviral Therapy.

Journal of immunology (Baltimore, Md. : 1950) 2017 12 08() pii 10.4049/jimmunol.1601254 Abstract IL-7 therapy has been evaluated in patients who do not regain normal CD4 T

Attention Deficit Hyperactivity Disorder (ADHD): Controversy, Developmental Mechanisms, and Multiple Levels of Analysis.

Annual review of clinical psychology 2017 12 08() doi 10.1146/annurev-clinpsy-050817-084917 Abstract Controversy abounds regarding the symptom dimensions of attention problems, impulsivity, and hyperactivity, developmentally extreme and impairing

Protocatechuic acid (PCA) induced a better antiviral effect by immune enhancement in SPF chickens.

Microbial pathogenesis 2017 12 05114() 233-238 pii 10.1016/j.micpath.2017.11.068 Abstract Protocatechuic acid (PCA) is an antiviral agent against Avian Influenza virus (AIV) and Infectious Bursal Disease (IBD) virus,

CRISPR/Cas9 delivery with one single adenoviral vector devoid of all viral genes.

Scientific reports 2017 12 077(1) 17113 doi 10.1038/s41598-017-17180-w Abstract The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 system revolutionized the field of gene editing but viral delivery

A randomized controlled safety/efficacy trial of therapeutic vaccination in HIV-infected individuals who initiated antiretroviral therapy early in infection.

Science translational medicine 9(419) pii 10.1126/scitranslmed.aan8848 Abstract Despite substantial clinical benefits, complete eradication of HIV has not been possible using antiretroviral therapy (ART) alone. Strategies that can

Simplification to dual-therapy containing lamivudine and darunavir/ritonavir or atazanavir/ritonavir in HIV-infected patients on virologically suppressive antiretroviral therapy.

Infectious diseases (London, England) 2017 12 06() 1-9 doi 10.1080/23744235.2017.1410285 Abstract BACKGROUND The ritonavir-boosted protease inhibitor (PI/r)-based dual regimens are warranted in order to optimize the combination

Facial Swelling and Foreign Body Granulomatous Reaction to Hyaluronic Acid Filler in the setting of Neratinib.

Journal of the European Academy of Dermatology and Venereology : JEADV 2017 12 10() doi 10.1111/jdv.14749 Abstract Cosmetic injection of dermal fillers is common, with late complications

Variations in the practice of molecular radiotherapy and implementation of dosimetry: results from a European survey.

EJNMMI physics 2017 12 044(1) 28 doi 10.1186/s40658-017-0193-4 Abstract BACKGROUND Currently, the implementation of dosimetry in molecular radiotherapy (MRT) is not well investigated, and in view of

Media Consumption and Creation in Attitudes Toward and Knowledge of Inflammatory Bowel Disease: Web-Based Survey.

Journal of medical Internet research 2017 12 0819(12) e403 doi 10.2196/jmir.7624 Abstract BACKGROUND Inflammatory bowel disease (IBD) is a chronic gastrointestinal condition affecting over 5 million people

Efavirenz is related to neuropsychiatric symptoms among adults, but not among adolescents living with HIV in Kilimanjaro, Tanzania.

Tropical medicine & international health : TM & IH 2017 12 08() doi 10.1111/tmi.13021 Abstract OBJECTIVES To explore the relationship between Efavirenz (EFV) and neuropsychiatric symptoms among

TNF-α induces expression of the circadian clock gene Bmal1 via dual calcium-dependent pathways in rheumatoid synovial cells.

Biochemical and biophysical research communications 2017 12 04() pii 10.1016/j.bbrc.2017.12.015 Abstract Tumor necrosis factor (TNF)-α is responsible for expressions of several clock genes and affects joint symptoms

Comparative typing analyses of clinical and environmental strains of the Cryptococcus neoformans/Cryptococcus gattii species complex from Ivory Coast.

Journal of medical microbiology 2017 12 07() doi 10.1099/jmm.0.000654 Abstract PURPOSE The aim of this study was to assess the biotope of the Cryptococcus neoformans/Cryptococcus gattii species

Clinical trial design: The nobility of randomization.

Science translational medicine 9(419) pii 10.1126/scitranslmed.aaq0810 Abstract A clinical trial evaluating HIV vaccine therapy teaches us much about optimal design (Sneller et al, this issue).

Effect of genetic variation in UGT1A and ABCB1 on moxifloxacin pharmacokinetics in South African patients with tuberculosis.

Pharmacogenomics 2017 12 06() doi 10.2217/pgs-2017-0144 Abstract AIM We assessed the effect of genetic variability in UGT1A and ABCB1 genes on moxifloxacin pharmacokinetics. METHODS Genotypes for selected UGT1A and ABCB1

TERT promoter hotspot mutations in breast cancer.

Breast cancer (Tokyo, Japan) 2017 12 08() doi 10.1007/s12282-017-0825-5 Abstract BACKGROUND Telomerase reverse transcriptase (TERT) promoter mutations have been discovered in solid and hematological malignancies, where they

Surgical Treatment of Superior Thyroid Artery Aneurysm with Concomitant Thyroid Cancer.

Chinese medical journal 130(23) 2885-2886 doi 10.4103/0366-6999.219145 Abstract

Drug delivery and tissue engineering to promote wound healing in the Immunocompromised host: Current challenges and future directions.

Advanced drug delivery reviews 2017 12 05() pii 10.1016/j.addr.2017.12.001 Abstract As regenerative medicine matures as a field, more promising technologies are being translated from the benchtop to

Hepatitis C Virus Genotyping of Organ Donor Samples to Aid in Transplantation of HCV-positive Organs.

Clinical transplantation 2017 12 08() doi 10.1111/ctr.13172 Abstract Given the availability of new highly efficacious anti-HCV therapies, some clinicians have advocated for wider use of kidneys from

Factors influencing the experience of sexual and reproductive healthcare for female adolescents with perinatally-acquired HIV: a qualitative case study.

BMC women’s health 2017 12 0817(1) 125 doi 10.1186/s12905-017-0485-9 Abstract BACKGROUND Young people living with perinatally-acquired HIV require age-appropriate support regarding sex and relationships as they progress

High HIV-1 RNA among Newly Diagnosed People in Botswana.

AIDS research and human retroviruses 2017 12 07() doi 10.1089/AID.2017.0214 Abstract OBJECTIVE HIV-1 RNA level is strongly associated with HIV transmission risk. We sought to determine whether

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