Proceedings of the National Academy of Sciences of the United States of America 2018 06 11115(26) 6822-6827 doi 10.1073/pnas.1806308115 Abstract Novel reassortant avian influenza H7N9 virus and pandemic 2009 H1N1 (H1N1pdm) virus...Read More
Nature communications 2018 06 069(1) 2197 doi 10.1038/s41467-018-04564-3 Abstract Eukaryotic cells employ the ribosome-associated quality control complex (RQC) to maintain homeostasis despite defects that cause ribosomes to...Read More
Nature communications 2018 06 309(1) 2447 doi 10.1038/s41467-018-04907-0 Abstract Signet-ring cell carcinoma (SRCC) has specific epidemiology and oncogenesis in gastric cancer, however, with no systematical investigation for...Read More
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
PloS one 2018 06 1813(6) e0198166 doi 10.1371/journal.pone.0198166 Abstract Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP)...Read More
eLife 2018 07 037() doi 10.7554/eLife.36402 Abstract Parkinson’s disease is a progressive neuropathological disorder that belongs to the class of synucleopathies, in which the protein alpha-synuclein is found at abnormally...Read More
International journal of molecular sciences 2018 06 0619(6) pii 10.3390/ijms19061689 Abstract Parkinson’s disease (PD) is a progressively debilitating neurodegenerative disease characterized by α-synucleinopathy, which involves...Read More
The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis.
Genes & development 2018 06 2732(13-14) 929-943 doi 10.1101/gad.313932.118 Abstract While a mutation in is the most common genetic contributor to amyotrophic lateral sclerosis (ALS), much remains to be learned concerning...Read More
Nature communications 2018 06 089(1) 2231 doi 10.1038/s41467-018-04651-5 Abstract CRISPR advances genome engineering by directing endonuclease sequence specificity with a guide RNA molecule (gRNA). For precisely targeting a gene...Read More
The New England journal of medicine 2018 06 25() doi 10.1056/NEJMoa1805233 Abstract Background In patients with diabetes, hospitalization can complicate the achievement of recommended glycemic targets. There is increasing...Read More