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Oncology

Efficacy of iron supplementation on fatigue and physical capacity in non-anaemic iron-deficient adults: a systematic review of randomised controlled trials.

BMJ open 2018 04 058(4) e019240 doi 10.1136/bmjopen-2017-019240 Abstract OBJECTIVE Iron supplementation in iron-deficiency anaemia is standard practice, but the benefits of iron supplementation in iron-deficient non-anaemic

Role of radiation therapy in primary breast diffuse large B-cell lymphoma in the Rituximab era: a SEER database analysis.

Cancer medicine 2018 04 06() doi 10.1002/cam4.1457 Abstract Primary breast diffuse large B-cell lymphoma (PB-DLBCL) is an uncommon extranodal non-Hodgkin’s lymphoma (NHL), which was traditionally treated with

Single and dual antiplatelet therapy in elderly patients of medically managed myocardial infarction.

BMC geriatrics 2018 04 0518(1) 86 doi 10.1186/s12877-018-0777-4 Abstract BACKGROUNDS To examine the comparative effectiveness between dual and single antiplatelet therapies in real-world, medically managed elderly patients

Dosimetric Implications of Computerised Tomography-Only versus Magnetic Resonance-Fusion Contouring in Stereotactic Body Radiotherapy for Prostate Cancer.

Medicines (Basel, Switzerland) 2018 04 055(2) pii 10.3390/medicines5020032 Abstract Magnetic resonance (MR)-fusion contouring is the standard of care in prostate stereotactic body radiotherapy (SBRT) for target volume

Therapeutic potential of heterocyclic pyrimidine scaffolds.

Chemistry Central journal 2018 04 0412(1) 38 doi 10.1186/s13065-018-0406-5 Abstract Heterocyclic compounds offer a high degree of structural diversity and have proven to be broadly and economically

In vivo study of non-invasive effects of non-thermal plasma in pressure ulcer treatment.

Scientific reports 2018 04 048(1) 5621 doi 10.1038/s41598-018-24049-z Abstract According to high incidence and prevalence of pressure ulcers worldwide, the purpose of this study is using of

Reoperation after breast-conserving surgery for cancer in Australia: statewide cohort study of linked hospital data.

BMJ open 2018 04 108(4) e020858 doi 10.1136/bmjopen-2017-020858 Abstract OBJECTIVES To investigate between-hospital variation in the probability of reoperation within 90 days of initial breast-conserving surgery (BCS),

GADD45A and CDKN1A are involved in apoptosis and cell cycle modulatory effects of viscumTT with further inactivation of the STAT3 pathway.

Scientific reports 2018 04 108(1) 5750 doi 10.1038/s41598-018-24075-x Abstract ViscumTT, a whole mistletoe preparation, has shown synergistic induction of apoptosis in several pediatric tumor entities. High therapeutic

Sesamin from Cuscuta palaestina natural plant extracts: Directions for new prospective applications.

PloS one 2018 04 1013(4) e0195707 doi 10.1371/journal.pone.0195707 Abstract The aim of this study is to disclose the potential bioactive components of Cuscuta palaestina, a native parasitic

Histone hypo-acetylation of Sox9 mediates nicotine-induced weak cartilage repair by suppressing BMSC chondrogenic differentiation.

Stem cell research & therapy 2018 04 109(1) 98 doi 10.1186/s13287-018-0853-x Abstract BACKGROUND Nicotine has negative effects on tissue repair, little research concerns its effect on the

STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle.

PLoS pathogens 2018 04 0914(4) e1006975 doi 10.1371/journal.ppat.1006975 Abstract Human papillomaviruses (HPV) activate a number of host factors to control their differentiation-dependent life cycles. The transcription factor

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers.

Cancer cell 2018 04 0233(4) 690-705.e9 pii 10.1016/j.ccell.2018.03.014 Abstract We analyzed molecular data on 2,579 tumors from The Cancer Genome Atlas (TCGA) of four gynecological types plus

Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer.

The New England journal of medicine 2018 02 08378(15) 1408-1418 doi 10.1056/NEJMoa1715546 Abstract BACKGROUND Apalutamide, a competitive inhibitor of the androgen receptor, is under development for the

Effects of Dietary Inorganic Nitrate Supplementation on Exercise Performance in Patients With Heart Failure: Protocol for a Randomized, Placebo-Controlled, Cross-Over Trial.

JMIR research protocols 2018 04 067(4) e86 doi 10.2196/resprot.8865 Abstract BACKGROUND Chronic heart failure is characterized by an inability of the heart to pump enough blood to

Antibiotic-mediated bacteriome depletion in Apcmice is associated with reduction in mucus-producing goblet cells and increased colorectal cancer progression.

Cancer medicine 2018 04 06() doi 10.1002/cam4.1460 Abstract Recent epidemiological evidence suggests that exposure to antibiotics in early-to-middle adulthood is associated with an increased risk of colorectal

Characteristics of Synchronous and Metachronous Multiple Gastric Tumors after Endoscopic Submucosal Dissection of Early Gastric Neoplasm.

Clinical endoscopy 2018 04 06() doi 10.5946/ce.2017.109 Abstract Background/Aims Endoscopic submucosal dissection (ESD) has been widely accepted as a method of treatment of early gastric tumor. This

Plants and Surgery: The Protective Effects of Thymoquinone on Hepatic Injury-A Systematic Review of In Vivo Studies.

International journal of molecular sciences 2018 04 0519(4) pii 10.3390/ijms19041085 Abstract Multimodal treatment concepts including liver transplantation for hepatocellular carcinoma (HCC), extended resection methods and neoadjuvant chemotherapy

Metabolomics of oncogene-specific metabolic reprogramming during breast cancer.

Cancer & metabolism 2018 04 036() 5 doi 10.1186/s40170-018-0175-6 Abstract Background The complex yet interrelated connections between cancer metabolism and oncogenic driver genes are relatively unexplored but

MiRNA-142-3p increases radiosensitivity in human umbilical cord blood mononuclear cells by inhibiting the expression of CD133.

Scientific reports 2018 04 048(1) 5674 doi 10.1038/s41598-018-23968-1 Abstract This study is to explore the molecular regulation mechanism of CD133 which is associated with malignancy and poor

Prevalence of Eosinophilic Esophagitis in Adult Patients with Upper Gastrointestinal Symptoms in a Locality in Upper Egypt.

Clinical endoscopy 2018 04 11() doi 10.5946/ce.2017.166 Abstract Background/Aims Eosinophilic esophagitis (EoE) is gaining importance in the diagnosis of upper gastrointestinal (UGI) symptoms. Diagnosis is based on

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