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The Impact of Flu Vaccination on Survival for Elderly Men With COPD

Jan 24, 2022

Previous studies have established that patients aged 65 and older with COPD are at elevated risk for influenza-associated complications, such as hospitalization, ICU admissions, and death. Guidelines ...

Pharmacists' views and desires regarding pharmacist administration of vaccines in New Zealand.

Mar 18, 2021

To explore pharmacists' views and experiences of pharmacist-administered vaccinations, motivators and barriers to pharmacists administering vaccinations and their preferences for expansions to such se...

VLP-factory™ and ADDomer : Self-assembling Virus-Like Particle (VLP) Technologies for Multiple Protein and Peptide Epitope Display.

Mar 18, 2021

Virus-like particles (VLPs) play a prominent role in vaccination as safe and highly versatile alternatives to attenuated or inactivated viruses or subunit vaccines. We present here two innovations, VL...

Effectiveness of influenza vaccination in infants and toddlers with and without prior infection history: The Japan Environment and Children's Study.

Mar 11, 2021

We calculated the Poisson-regression-adjusted relative risk (RR) of new influenza infection by vaccination, prior infection, and vaccination after prior infection in a large Japanese birth cohort, usi...

Identifying the commonly used antibiotics for self-medication in urban Mozambique: a qualitative study.

Dec 31, 2020

The study aimed at identifying the commonly used non-prescribed antibiotics (NPAs) and the main health conditions leading to the practices of self-medication with antibiotics (SMAs) in Maputo city, Mo...

Time series computational prediction of vaccines for influenza A H3N2 with recurrent neural networks.

Apr 28, 2020

Influenza viruses are persistently threatening public health, causing annual epidemics and sporadic pandemics due to rapid viral evolution. Vaccines are used to prevent influenza infections but the co...

On the global trends and spread of the COVID-19 outbreak: preliminary assessment of the potential relation between location-specific temperature and UV index.

Apr 28, 2020

The novel coronavirus, since its first outbreak in December, has, up till now, affected approximately 114,542 people across 115 countries. Many international agencies are devoting efforts to enhance t...

Quantification of the sensitivity of early detection surveillance.

Apr 28, 2020

Early detection surveillance is used for various purposes, including the early detection of non-communicable diseases (e.g., cancer screening), of unusual increases of disease frequency (e.g., influen...

INFECTIONS IN PREGNANCY WITH COVID-19 AND OTHER RESPIRATORY RNA VIRUS DISEASES ARE RARELY, IF EVER, TRANSMITTED TO THE FETUS: EXPERIENCES WITH CORONAVIRUSES, HPIV, hMPV RSV, AND INFLUENZA.

Apr 28, 2020

SARS-CoV-2, the agent of COVID-19, is similar to two other coronaviruses, SARS-CoV and MERS-CoV, in causing life-threatening maternal respiratory infections and systemic complications. Because of glob...

Investigation of a Cluster of Severe Respiratory Disease Referred from Uganda to Kenya, February 2017.

Apr 24, 2020

On February 22, 2017, Hospital X-Kampala and US CDC-Kenya reported to the Uganda Ministry of Health a respiratory illness in a 46-year-old expatriate of Company A. The patient, Mr. A, was evacuated fr...

The efficacy and safety of bisphosphonates for osteoporosis in women older than 65 years: a meta-analysis.

Apr 24, 2020

Osteoporosis presents a major threat to the health of women older than 65 years. Bisphosphonates (BPs) are now the principal class of medications for osteoporosis.To evaluate the efficacy and safety o...

Comparison of influenza hospitalization outcomes among adults, older adults, and octogenarians: A US national population-based study.

Apr 24, 2020

This study sought to more fully elucidate the age-related trends in influenza mortality with a secondary goal of uncovering implications for treatment and prevention.In this retrospective cohort analy...

An international cohort study of birth outcomes associated with hospitalized acute respiratory infection during pregnancy.

Apr 24, 2020

Findings during the 2009 pandemic suggest severe maternal infection with pandemic influenza had adverse perinatal health consequences. Limited data exist evaluating the perinatal health effects of sev...

Prevention of influenza virus infection and transmission by intranasal administration of a porous maltodextrin nanoparticle-formulated vaccine.

Apr 24, 2020

Influenza vaccines administered intramuscularly exhibit poor mucosal immune responses in the respiratory tract which is the prime site of the infection. Intranasal vaccination is a potential route for...

Exploring the Relevance of Senotherapeutics for the Current SARS-CoV-2 Emergency and Similar Future Global Health Threats.

Apr 12, 2020

The higher death rate caused by COVID-19 in older people, especially those with comorbidities, is a challenge for biomedical aging research. Here we explore the idea that an exacerbated inflammatory r...

Negative effect on immune response of repeated influenza vaccination and waning effectiveness in interseason for elderly people.

Apr 12, 2020

Through test negative designs for visiting a doctor because of influenza-like illness, many studies have found decreasing efficacy of repeated vaccination. Furthermore, waning effectiveness during int...

A method to prevent SARS-CoV-2 IgM false positives in gold immunochromatography and enzyme-linked immunosorbent assays.

Apr 12, 2020

To investigate the interference factors that lead to false-positive novel coronavirus (SARS-CoV-2) IgM detected using gold immunochromatography assay (GICA) and enzyme-linked immunosorbent assay (ELI...

Cluster of coronavirus disease 2019 (Covid-19) in the French Alps, 2020.

Apr 12, 2020

On 07/02/2020, French Health authorities were informed of a confirmed case of SARS-CoV-2 coronavirus in an Englishman infected in Singapore who had recently stayed in a chalet in the French Alps. We c...

Cytokine Storm: The Sudden Crash in Patients with COVID-19

Apr 08, 2020

It's jarring every time. The sudden crash in patients with COVID-19 All over the world, seemingly mild cases of COVID-19 rapidly morph into severe cases that involve the lower lungs. This may b...

What cells does the novel coronavirus attack?

Apr 07, 2020

Scientists from the Berlin Institute of Health (BIH), Charité - Universitätsmedizin Berlin and the Thorax Clinic at Heidelberg University Hospital, whose collaboration is taking place under the ...