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Pulmonology General

Clinical Utility of Liquid Biopsy cfDNA-based EGFR Mutation Detection

Jun 08, 2022

For a study, researchers sought to investigate the utility of Liquid Biopsy cfDNA-based epidermal growth factor receptor (EGFR) mutation testing in patients with non-small cell lung cancer (NSCLC) as ...

Immunotherapy-based Systemic Therapy With or Without SBRT in Patients

Jun 07, 2022

Immunotherapy was often less effective in patients who did not exhibit the protein Programmed Death-Ligand 1 (PD-L1). Combined with systemic therapy, including immunotherapy, this trial saw if stereot...

Non-Small Cell Lung Cancer Patients: ICI Monotherapy

Jun 07, 2022

Chemotherapy coupled with ICI has been proven to provide positive results. On the other hand, ICI monotherapy was still a viable treatment choice. However, there were few long-term progression-free su...

Non-Small-Cell Lung Cancer: Treatment Delay & Survival

Jun 07, 2022

For a study, researchers sought to determine how long postponing therapy for stage III-IV non-small-cell lung cancer affected patient survival. Cox regression analysis with penalized smoothing splines...

Neoadjuvant Pre-Habilitation Therapy: Non-Small-Cell Lung Cancer

Jun 07, 2022

For a study, researchers sought to look at non-small-cell lung cancer patients who received pre-habilitation and neoadjuvant therapy simultaneously in this proof-of-concept research. Between 2015 and ...

Total Lymph Nodes & Lymph Node Ratio to Determine the Indications

Jun 07, 2022

Researchers believed that Postoperative radiation (PORT) could increase overall survival (OS) in patients with pN2 NSCLC who have a high lymph node ratio (LNR). From 2004 to 2016, the National Cancer ...

Patterns of Failure & Optimal Treatment Paradigm NSCLC

Jun 06, 2022

For a study, the researchers sought to look at patterns of failure and the impact of receiving radiation therapy (RT) and chemotherapy to help themselves figure out the best treatment options for the ...

NFE2L2 & KEAP1 Mutation-Positive Advanced Squamous Cell NSCLC

Jun 06, 2022

Researchers used NFE2L2 and KEAP1 mutation status to evaluate real-world survival outcomes and treatment patterns in patients with advanced squamous cell NSCLC. A retrospective analysis utilized a de-...

Small Cell Lung Cancers (SCLCs) With Short Survival Subgroup

Jun 06, 2022

There were no clinically significant predictors of therapy response, and therapeutic alternatives were restricted. For 108 SCLCs, clinical data and somatic mutations of MSK-IMPACT panel genes were col...

Dostarlimab's Safety & Efficacy in Patients with NSCLC

Jun 06, 2022

For a study, researchers sought to understand that Dostarlimab, a PD-1 inhibitor, showed anticancer efficacy in 67 patients with recurrent/advanced NSCLC in a Phase I trial, with an irORR of 26.9% (2 ...

A Standardized Approach to Improve COPD Care in the ED

May 27, 2022

Adherence to guidelines for COPD in an ED setting can help patients avoid compromising their health-related quality of life. Evidence suggests that adherence to COPD guidelines in the ED can he...

[Parenthood challenged by cystic fibrosis. Experience of affected parents].

May 23, 2022

Medical progress affords patients with cystic fibrosis (CF) the opportunity to become parents.To assess the psychological issues of parenthood in persons with cystic fibrosis.Semi-structured interview...

Osteoporosis in nontuberculous mycobacterial pulmonary disease: a cross-sectional study.

May 23, 2022

Since nontuberculous mycobacterial pulmonary disease (NTM-PD) is common in middle-aged/elderly slender women at risk of osteoporosis, we hypothesized that NTM-PD could be associated with osteoporosis....

Prior Inhaled Corticosteroid Use & Benefits of BGFF in COPD Patients

May 20, 2022

In the Phase III ETHOS study (NCT02465567), budesonide/glycopyrronium/formoterol fumarate dihydrate (BGF) triple therapy at two inhaled corticosteroid (ICS) doses reduced moderate/severe exacerbation ...

Clinical Information Predicting Severe Obstructive Sleep Apnea (OSA)

May 20, 2022

Obstructive sleep apnea (OSA) is extremely common and has major health repercussions. Demand for diagnostic investigations is surpassing capacity in several nations. For a cross-sectional study, resea...

Silent Hypoxia in Patients With COVID-19 Infection

May 20, 2022

For a study, researchers sought to see if asymptomatic ("happy") hypoxia was a distinct physiological feature of COVID-19 ARDS and if it was connected with the requirement for ICU admission. They cond...

Macklin Effect on Baseline Chest CT Scan Predicts Barotrauma in COVID-19 Patients

May 20, 2022

For a study, researchers sought to confirm the role of the Macklin effect on chest CT imaging in predicting the development of pneumomediastinum/pneumothorax (PMD/PNX) in COVID-19 patients. It was a c...

Pre-Transplant Malignancy is Associated With Risk of De Novo Malignancy Post-Lung Transplantation

May 19, 2022

Within 5 years following their transplant, at least 20% of lung transplant patients will be diagnosed with cancer. Transplant candidates with a history of pre-transplant malignancy must achieve remiss...

Prognostic Value of Key Variables From Cardiopulmonary Exercise Testing in COPD Patients

May 19, 2022

Using possible predictors derived from key measurements collected from cardiopulmonary exercise testing (CPET), improved predictors of early death in patients with chronic obstructive pulmonary diseas...

Ambulatory Patients With Suspected COVID-19 At A Respiratory Referral Centre

May 19, 2022

SARS-CoV-2 continues to spread over the world, and COVID-19 care in outpatient settings is difficult. Prior to widely available testing, the emergence of variants, COVID-19 vaccination, and post-vacci...