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Arthritis

One-Leg Stand Is Useful Tool for Assessing Fall Risk in RA

Aug 09, 2022

The one-leg stand could have value as a prognostic tool for fall risk in patients with rheumatoid arthritis, despite safety concerns for some patients. Studies have shown that people with rheum...

Unmet Therapeutic Needs Observed for Patients With Lupus

Jun 16, 2022

Unmet therapeutic needs in patients with systemic lupus erythematosus is a widespread and serious issue that urgently needs to be addressed Understanding whether patients with systemic lupus er...

Association Between IgG N-glycosylation & Rheumatoid Arthritis

Jun 10, 2022

Observational studies have linked IgG N-glycosylation to rheumatoid arthritis (RA), but the causal relationship between the 2 illnesses has yet to be established. To investigate the possible causal co...

Conference Highlights: EULAR 2022

Jun 07, 2022

New research was presented at EULAR 2022, the European Alliance for Associations for Rheumatology Annual Meeting, from June 1-4 in Copenhagen, Denmark, and virtually. The features below highlight some...

Intra-articular opening wedge osteotomy for varus ankle arthritis with computer-assisted planning and patient-specific surgical guides: a retrospective case series.

May 23, 2022

Computer-assisted preoperative planning, combined with PSI has become an effective technique for treating complex limb deformities. The purpose of this study was to evaluate the efficacy and safety of...

Can metformin relieve tibiofemoral cartilage volume loss and knee symptoms in overweight knee osteoarthritis patients? Study protocol for a randomized, double-blind, and placebo-controlled trial.

May 23, 2022

Osteoarthritis (OA) is the most common joint disease, and is most frequently seen in the knees. However, there is no effective therapy to relieve the progression of knee OA. Metformin is a safe, well-...

Positivity rates of mycobacterial culture in patients with tuberculous spondylitis according to methods and sites of biopsies: An analysis of 206 cases.

May 16, 2022

We aimed to evaluate the mycobacterial culture positivity rates according to biopsy methods and sites in patients with tuberculous spondylitis (TS) and identify which tissues are the best sites for di...

The effects of total knee arthroplasty on knee proprioception of patients with knee osteoarthritis: a meta-analysis.

May 09, 2022

Studies have given some pieces of evidence for the effect of total knee arthroplasty (TKA) on knee proprioception of patients with knee osteoarthritis (KOA), but their results were conflicting. This r...

Opsonized nanoparticles target and regulate macrophage polarization for osteoarthritis therapy: A trapping strategy.

May 02, 2022

Osteoarthritis (OA) is a chronic disease caused by joint inflammation. Its occurrence and development depend on a continuous inflammation environment. The activated M1 macrophages play a critical role...

Monoamine oxidase A attenuates chondrocyte loss and extracellular matrix degradation in osteoarthritis by inducing autophagy.

Apr 25, 2022

Osteoarthritis (OA) is a prevalent degenerative joint disorder characterized by cartilage destruction and extracellular matrix (ECM) degeneration. Here, we studied the potential function of monoamine ...

Dopamine-conjugated hyaluronic acid delivered via intra-articular injection provides articular cartilage lubrication and protection.

Apr 11, 2022

Due to its high molecular weight and viscosity, hyaluronic acid (HA) is widely used for viscosupplementation to provide joint pain relief in osteoarthritis. However, this benefit is temporary due to p...

Changes in ankle and foot kinematic after fixed-bearing total ankle replacement.

Apr 04, 2022

Ankle osteoarthritis is a chronic debilitating disease marked by cartilage breakdown, pain and significant biomechanical impairment of the entire lower limb. Total ankle replacement (TAR) has been enc...

Knee & Hip Osteoarthritis: More Alike Than Different

Mar 29, 2022

“Clinicians who treat patients with osteoarthritis share a common perception that patients with knee osteoarthritis (OA) have better outcomes from exercise than those with hip OA,” explains Ewa M....

Psoriatic Disease & Risk for Cardiovascular Disease

Mar 28, 2022

Patients with psoriasis and psoriatic arthritis (PsA) are at high risk for developing cardiovascular (CV) diseases, explains Lihi Eder, MD, PhD. “Primary prevention measures, such as initiation of l...

Integration of polyurethane meniscus scaffold during ACL revision is not reliable at 5 years despite favourable clinical outcome.

Mar 28, 2022

The aim of this study was to evaluate the clinical outcome at 5-year follow-up of a one-step procedure combining anterior cruciate ligament (ACL) reconstruction and partial meniscus replacement using ...

External validation of an artificial intelligence tool for radiographic knee osteoarthritis severity classification.

Mar 28, 2022

To externally validate an artificial intelligence (AI) tool for radiographic knee osteoarthritis severity classification on a clinical dataset.This retrospective, consecutive patient sample, external ...

Online information about the management of anterior cruciate ligament ruptures in Australia: A content analysis.

Mar 21, 2022

Most people who suffer an anterior cruciate ligament (ACL) injury search for information online.Summarise the proportion of webpages on ACL rupture management that present evidence-based information.C...

Early Outcome of Humeral Head Replacement with Glenoid Reaming Arthroplasty (Ream and Run) for Treatment of Advanced Glenohumeral Osteoarthritis.

Mar 14, 2022

Long-term outcomes of anatomic total shoulder arthroplasty (aTSA) can be compromised by glenoid loosening and failure. The purpose of this study was to evaluate the short- and mid-term outcomes of hum...

Intra-articular injection of a novel Wnt pathway inhibitor, SM04690, upregulates Wnt16 expression and reduces disease progression in temporomandibular joint osteoarthritis.

Feb 28, 2022

Abnormal Wnt signaling has been shown to be involved in the pathogenesis of temporomandibular joint osteoarthritis (TMJOA). Recent studies demonstrates that SM04690, a small-molecule inhibitor of the ...

A new HClO-activated "turn-off" mitochondria-targetable NIR fluorescent probe for imaging of osteoarthritis in vivo.

Feb 21, 2022

Hypochlorous acid (HClO) as a biomarker of inflammation has been implicated in redox signaling and combating microbial infection. Therefore, it is of great significance to develop an efficient method ...