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Rheumatology General

M2 Macrophages, Th2, & B Cells With Pathomechanism in MPA Complicated by ILD

Aug 09, 2022

Using the serum biomarker profile and pulmonary histopathology, researchers sought to investigate the pathomechanism of microscopic polyangiitis (MPA) worsened by interstitial lung disease (ILD). T...

Rho Kinase Expression in GCA: Validating pERM Intensity Score to Increase Sensitivity of TABs

Aug 09, 2022

Countless vascular and immunologic disorders are linked to aberrant Rho-associated protein kinase (ROCK) activity. Previously, researchers found that patients with clinical giant cell arteritis (GCA) ...

PASS for Burden From Appearance Changes in Systemic Sclerosis Patients

Aug 09, 2022

Many people with systemic sclerosis (SSc) describe feeling a lot of burden from physical changes. For a study, researchers sought to determine the patient acceptable symptom state (PASS) for the burde...

Secukinumab in American Biologic-Naïve Psoriatic Arthritis Patients

Aug 09, 2022

For a study, researchers sought to compare the effectiveness of secukinumab (SEC) 300 mg and 150 mg against a placebo in a group of psoriatic arthritis (PsA) patients who had never taken a biologic. ...

Psoriatic Arthritis (PsA): Sex and BMI Potential Impact on Response to Therapy

Aug 09, 2022

In the Study of Etanercept and Methotrexate in Combination or as Monotherapy in Subjects with Psoriatic Arthritis (SEAM-PsA), a 48-week, phase III, randomized controlled trial that compared outcomes w...

Monitoring Disease Activity in axSpA Patients Having Routine Clinical Care Using a Smartphone App

Aug 09, 2022

For a study, researchers sought to examine how well a health app performs in terms of usability, adherence, and data equivalency in the daily management of patients with axial spondyloarthritis (axSpA...

Whole-Body Macrophage PET Imaging for Early RA Disease Activity Assessmen

Aug 09, 2022

For a study, researchers sought to find out if early rheumatoid arthritis (RA) patients may have whole-body positron emission tomography/computed tomography (PET/CT) with a macrophage tracer to scan t...

Tofacitinib and TNFi in RA: Physician-and Patient-reported Effectiveness

Aug 01, 2022

Tofacitinib (TOF) is a small-molecule medication taken orally to treat rheumatoid arthritis (RA). It is numerous alternatives to tumor necrosis factor inhibitors (TNFi). Using real-world data from the...

RTX Treatment for Developing a Humoral Response to COVID-19 mRNA Vaccines in RD Patients

Aug 01, 2022

For a study, researchers sought to determine if individuals with a rheumatic disease (RD) who were given rituximab (RTX) had a serological response to the coronavirus disease 2019 (COVID-19) mRNA vacc...

Results of the Workforce & Wellness Survey from the CRA

Aug 01, 2022

The Canadian Rheumatology Association (CRA) sponsored the Workforce and Wellness Survey to update the characteristics of the Canadian rheumatology workforce. The survey comprised demographic and pr...

Polymyalgia Rheumatica Activity Score (PMR-AS) Measurement Properties

Aug 01, 2022

For a study, researchers sought to conduct a systematic assessment of the measurement qualities of the Polymyalgia Rheumatica Activity Score (PMR-AS) using the Consensus-based Standards for the Select...

WOMAC Meaningful Within-patient Change (MWPC): Results From 3 Studies of Tanezumab

Aug 01, 2022

For a study, researchers sought to identify meaningful within-patient change (MWPC) in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Data from three phase III clinical...

Achievement of cDAPSA Treatment Targets With Apremilast in DMARD-naïve PsA Patients

Aug 01, 2022

Based on baseline disease activity, the likelihood of achieving Clinical Disease Activity Index for Psoriatic Arthritis (cDAPSA) treatment targets (remission [REM], low disease activity [LDA]) was ass...

Why Don't Gout Patients Take Allopurinol?

Aug 01, 2022

For a study, researchers sought to determine the reasons patients provide for not taking allopurinol and to see if there were any differences in intentional nonadherence between patients who did and d...

Secukinumab’s 6-month Efficacy in PsA Patients in the CorEvitas PsA/Spondyloarthritis Registry

Aug 01, 2022

For a study, researchers sought to assess clinical and patient-reported outcomes (PROs) 6 months after starting secukinumab in psoriatic arthritis (PsA) patients in the United States. Patients with...

Mortality Rates in Ankylosing Spondylitis Patients: With and Without EAMs & Comorbidities

Aug 01, 2022

For a study, researchers sought to determine the mortality rates in hospitalized patients with ankylosing spondylitis (AS) and the relationship between EAMs, comorbidities, and death rates. It was ...

Previously Undiagnosed axSpA in Anterior Uveitis and CBP Patients

Aug 01, 2022

Guidelines encourage sending individuals with acute anterior uveitis (AAU) and chronic back pain (CBP) to a rheumatologist to decrease the diagnosis delay in axial spondyloarthritis (axSpA). For obser...

Rheumatoid Arthritis-related Bronchiectasis Risk Factors

Aug 01, 2022

For a study, researchers sought to determine the demographic, lifestyle, and serologic risk factors for isolated rheumatoid arthritis (RA)-associated bronchiectasis (RA-BR) that was not caused by inte...

Rheumatoid Arthritis (RA) Autoantibodies are Present in Male and Female

Jul 29, 2022

Although the etiology of RA is uncertain, it is defined by the generation of autoantibodies. For a study, researchers sought to determine if females had more RA-related autoantibodies than males and t...

Health Literacy and Numeracy With Lupus Knowledge & the Creation of the LKAT

Jul 28, 2022

Limited health literacy and numeracy are related to poorer patient-reported outcomes and increased disease activity in systemic lupus erythematosus (SLE). However, it was unclear which variables may m...