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Rheumatology General

Mannose Binding Lectin Levels and its Association with Systemic Lupus Erythematosus Disease Severity: An Indian Report.

May 23, 2022

Dysregulated serum levels of Mannan binding lectin (MBL) has a probable role in Systemic Lupus Erythematosus (SLE) pathogenesis.To evaluate the association between serum MBL levels in SLE patients fro...

Intra-articular opening wedge osteotomy for varus ankle arthritis with computer-assisted planning and patient-specific surgical guides: a retrospective case series.

May 23, 2022

Computer-assisted preoperative planning, combined with PSI has become an effective technique for treating complex limb deformities. The purpose of this study was to evaluate the efficacy and safety of...

Can metformin relieve tibiofemoral cartilage volume loss and knee symptoms in overweight knee osteoarthritis patients? Study protocol for a randomized, double-blind, and placebo-controlled trial.

May 23, 2022

Osteoarthritis (OA) is the most common joint disease, and is most frequently seen in the knees. However, there is no effective therapy to relieve the progression of knee OA. Metformin is a safe, well-...

Rising incidence and prevalence of systemic lupus erythematosus: a population-based study over four decades.

May 23, 2022

To determine the trends in incidence, prevalence and mortality of systemic lupus erythematosus (SLE) in a US population over four decades.We identified all the patients with SLE in Olmsted County, Min...

Increased frequency of activated regulatory T cells in patients with lupus nephritis.

May 16, 2022

Lupus nephritis (LN) is one of the common manifestations of SLE, which affects the quality of life of patients. Abnormality in the adaptive immune response, such as T cell response, plays the main rol...

Mobile health apps for systemic lupus erythematosus and lupus nephritis: a critical appraisal.

May 16, 2022

To critically assess the quality and functionality of the available mobile apps for systemic lupus erythematosus and lupus nephritis patients.Two reviewers independently searched the App Store and Goo...

(Fibro Friends): Validation of an Educational Program to Promote Health in Fibromyalgia.

May 16, 2022

Health education is one of the main items to enable the promotion of health for individuals with fibromyalgia (FM) in Primary Health Care (PHC) in Brazil. The purpose of this study was to validate a m...

Diffuse Peripheral Enthesitis in Metabolic Syndrome: A Retrospective Clinical and Power Doppler Ultrasound Study.

May 16, 2022

To investigate peripheral enthesitis with power Doppler ultrasound (PDUS) in patients presenting low back pain (LBP) and metabolic syndrome (MetS) in comparison with patients with only LBP, to correla...

Positivity rates of mycobacterial culture in patients with tuberculous spondylitis according to methods and sites of biopsies: An analysis of 206 cases.

May 16, 2022

We aimed to evaluate the mycobacterial culture positivity rates according to biopsy methods and sites in patients with tuberculous spondylitis (TS) and identify which tissues are the best sites for di...

Melatonin alleviates the immune response and improves salivary gland function in primary Sjögren's syndrome.

May 09, 2022

Primary Sjögren's syndrome (pSS) is an autoimmune disease that primarily affects exocrine glands and is characterized by sicca syndrome and systemic manifestation. Mounting evidence indicates that ci...

Responsiveness of the Zurich Claudication Questionnaire, the Oswestry Disability Index, the Japanese Orthopaedic Association Back Pain Evaluation Questionnaire, the 8-Item Short Form Health Survey, and the Euroqol 5 dimensions 5 level in the assessment of patients with lumbar spinal stenosis.

May 09, 2022

To assess the responsiveness of the Zurich Claudication Questionnaire (ZCQ), the Oswestry Disability Index, the Japanese Orthopaedic Association Back Pain Evaluation Questionnaire, the visual analog s...

Ventral Intrameningeal Cyst Treatment and Management: Technical Note.

May 09, 2022

Intrameningeal cysts are rare lesions without definitive etiologies that can involve the dura or arachnoid mater. Spinal arachnoid cysts have been described, and several different etiologies have been...

The effects of total knee arthroplasty on knee proprioception of patients with knee osteoarthritis: a meta-analysis.

May 09, 2022

Studies have given some pieces of evidence for the effect of total knee arthroplasty (TKA) on knee proprioception of patients with knee osteoarthritis (KOA), but their results were conflicting. This r...

Which psychosocial factors are related to severe pain and functional limitation in patients with low back pain?: Psychosocial factors related to severe low back pain.

May 02, 2022

Low back pain (LBP) is a global public health issue. Psychosocial factors are linked to LBP. However, there is a lack of knowledge about the relation of psychosocial factors to clinical outcomes of pa...

Percutaneous Endoscopic Lumbar Discectomy for Lumbar Disc Herniation with Type II Modic Changes.

May 02, 2022

Percutaneous endoscopic lumbar discectomy (PELD) has become a favorable surgical approach for lumbar radiculopathy caused by intervertebral disc herniation. Studies have revealed patients with type II...

Opsonized nanoparticles target and regulate macrophage polarization for osteoarthritis therapy: A trapping strategy.

May 02, 2022

Osteoarthritis (OA) is a chronic disease caused by joint inflammation. Its occurrence and development depend on a continuous inflammation environment. The activated M1 macrophages play a critical role...

The dynamics of Th17 / Treg ratio in SLE patients during pregnancy.

Apr 25, 2022

Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disorder that affects women at childbearing age. During pregnancy, maternal immune system is challenged to tolerate a semi-allogenic fe...

Comparative evaluation of the effectiveness of intravenous paracetamol, dexketoprofen and ibuprofen in acute low back pain.

Apr 25, 2022

Non-traumatic back pain constitutes roughly 5% of the admissions to emergency departments. This study seeks to compare the efficacy of intravenously administered paracetamol, dexketoprofen, and ibupro...

Monoamine oxidase A attenuates chondrocyte loss and extracellular matrix degradation in osteoarthritis by inducing autophagy.

Apr 25, 2022

Osteoarthritis (OA) is a prevalent degenerative joint disorder characterized by cartilage destruction and extracellular matrix (ECM) degeneration. Here, we studied the potential function of monoamine ...

Rheumatoid Arthritis Has Similar Rates of Postpartum Maternal Outcomes

Apr 18, 2022

The impact of rheumatoid arthritis (RA) on maternal postpartum outcomes was little understood. Researchers evaluated maternal postpartum outcomes in RA using a real-world electronic health record (EHR...