Catastrophic antiphospholipid syndrome (CAPS) is a rare disorder characterized by a storm of thrombosis leading to rapidly progressive multiple organ damage and thus needs to be picked earlier in the course of the disease. A...
We studied the rate of remission of lupus nephritis (LN) in an international cohort of 248 children and adolescents with biopsy proven LN. Five different definitions from scientific studies and the definitions recommended by the...
Systemic lupus erythematosus (SLE) is an autoimmune disorder in which the body’s defense system wrongly attacks healthy body tissues. The objective of this current setup was to quantify and compare the serum concentration...
Vitamin D receptor (VDR) and NLRP3 inflammasome play critical roles in lupus nephritis (LN) pathogenesis.This study explored the therapeutic effect of VDR agonist on LN and its molecular mechanism to inhibit NLRP3...
There continues to be rapid advancement in the understanding of pathogenesis of immune mediated kidney disease. This progress has culminated into development of multiple therapeutic agents that have consistently improved renal...
Tubular basement membrane (TBM) deposits are very uncommon in non-lupus membranous nephropathy. We report a series of 5 patients with membranous nephropathy and extensive TBM deposits following allogeneic hematopoietic cell...
The objective of this meta-analysis was to review the diagnostic performance of anti-dsDNA testing, to determine whether test specificity meets the revised 2019 EULAR/ACR classification criteria for systemic lupus erythematosus...
Recent studies indicate that Toll-like receptors (TLRs) and C-type lectin receptors (CLRs) can function as the signal of pattern recognition receptors, which play a pivotal role in the pathogenesis of the autoimmune disease....
Coronavirus disease 2019 (COVID-19) possesses a substantial challenge for rheumatologists and rheumatologic patients. They are concerned about the reciprocal interaction between connective tissue diseases, such as systemic lupus...
To explore the clinical and pathological features, therapy and prognosis of Castleman’s disease (CD) in the head and neck.We retrospectively analyzed the clinical and pathological data of 44 patients with head and neck CD...
Alteration of the gut microbiome has been linked to the pathogenesis of systemic lupus erythematosus (SLE). However, a comprehensive view of the gut microbiome in SLE and its interaction with the host remains to be revealed....
Previous studies on the association between atopic dermatitis (AD) and systemic lupus erythematosus (SLE) have yielded inconsistent results.To investigate the relationship between atopic dermatitis and systemic lupus...
