Atherosclerosis Events in SLE
Previous research suggests that patients with systemic lupus erythematosus (SLE) have a high risk...
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Lupus
Systematic review of observational studies reporting antiphospholipid antibodies in patients with solid tumors.
This review summarizes the evidence on antiphospholipid (aPL) antibodies and related thromboembolic events in patients with solid tumors. Data sources included Medline, EMBASE, Web of Science, PubMed ePubs, and the Cochrane...
Read MoreNeuromyelitis Optica and Systemic Lupus Erythematosus Association – the Chicken or the Egg Dilemma: a Case Repor.
We present a case report of a 32-year-old woman diagnosed with opticomyelitis of Devic (OMD) and systemic lupus erythematosus (SLE). The onset of neurological symptoms was with optic neuritis. Five months later the neurological...
Read MoreAutoantibodies against the autophagic protein microtubule-associated light-chain 3 (LC3): Immunocharacterization of an atypical ANA pattern.
Autoantibodies to nuclear and cytoplasmic antigens are commonly detected by indirect immunofluorescence (IIF) on HEp-2 cells, and three major staining patterns (nuclear, cytoplasmic, and mitotic) are distinguished. Here, we...
Read MoreTopical delivery of siRNA into skin using ionic liquids.
Skin diseases such as lupus, cancer, psoriasis, hyperhidrosis can potentially be treated effectively by suppressing allele-specific genes using small interfering RNA (siRNA). Injections of siRNA into skin, though effective, are...
Read MoreUpstream ORFs Prevent MAVS Spontaneous Aggregation and Regulate Innate Immune Homeostasis.
The monomer-to-filament transition of MAVS is essential for the RIG-I/MDA5-mediated antiviral signaling. In quiescent cells, monomeric MAVS is under strict regulation for preventing its spontaneous aggregation, which would...
Read MorePsoriasis and systemic lupus erythematosus in children – literature review based on case report.
Immune-mediated inflammatory diseases are a group of diseases characterized by generalized inflammation that results from immune dysregulation, especially involving the mechanisms of acquired immunity. These diseases may be...
Read MoreClinical Efficacy and Safety of Mesenchymal Stem Cells for Systemic Lupus Erythematosus.
Systemic lupus erythematosus (SLE) is a polymorphic, multisystemic autoimmune disease that causes multiorgan damage in which cellular communication occurs through the involvement of autoantibodies directed against autoantigen...
Read MoreSubjective and Objective Measurements of Sinonasal Manifestations in Patients With Autoimmune Disorders.
A number of autoimmune disorders (ADs) are associated with a spectrum of sinonasal manifestations comparable to chronic rhinosinusitis (CRS). Our objective was to study the subjective and objective measurements of sinonasal...
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