Atherosclerosis Events in SLE
Previous research suggests that patients with systemic lupus erythematosus (SLE) have a high risk...
Lupus
Systematic review of observational studies reporting antiphospholipid antibodies in patients with solid tumors.
This review summarizes the evidence on antiphospholipid (aPL) antibodies and related thromboembolic events in patients with solid tumors. Data sources included Medline, EMBASE, Web of Science, PubMed ePubs, and the Cochrane...
Neuromyelitis Optica and Systemic Lupus Erythematosus Association – the Chicken or the Egg Dilemma: a Case Repor.
We present a case report of a 32-year-old woman diagnosed with opticomyelitis of Devic (OMD) and systemic lupus erythematosus (SLE). The onset of neurological symptoms was with optic neuritis. Five months later the neurological...
Autoantibodies against the autophagic protein microtubule-associated light-chain 3 (LC3): Immunocharacterization of an atypical ANA pattern.
Autoantibodies to nuclear and cytoplasmic antigens are commonly detected by indirect immunofluorescence (IIF) on HEp-2 cells, and three major staining patterns (nuclear, cytoplasmic, and mitotic) are distinguished. Here, we...
Topical delivery of siRNA into skin using ionic liquids.
Skin diseases such as lupus, cancer, psoriasis, hyperhidrosis can potentially be treated effectively by suppressing allele-specific genes using small interfering RNA (siRNA). Injections of siRNA into skin, though effective, are...
Upstream ORFs Prevent MAVS Spontaneous Aggregation and Regulate Innate Immune Homeostasis.
The monomer-to-filament transition of MAVS is essential for the RIG-I/MDA5-mediated antiviral signaling. In quiescent cells, monomeric MAVS is under strict regulation for preventing its spontaneous aggregation, which would...
Psoriasis and systemic lupus erythematosus in children – literature review based on case report.
Immune-mediated inflammatory diseases are a group of diseases characterized by generalized inflammation that results from immune dysregulation, especially involving the mechanisms of acquired immunity. These diseases may be...
Clinical Efficacy and Safety of Mesenchymal Stem Cells for Systemic Lupus Erythematosus.
Systemic lupus erythematosus (SLE) is a polymorphic, multisystemic autoimmune disease that causes multiorgan damage in which cellular communication occurs through the involvement of autoantibodies directed against autoantigen...
Subjective and Objective Measurements of Sinonasal Manifestations in Patients With Autoimmune Disorders.
A number of autoimmune disorders (ADs) are associated with a spectrum of sinonasal manifestations comparable to chronic rhinosinusitis (CRS). Our objective was to study the subjective and objective measurements of sinonasal...
[Antinuclear antibodies in systemic autoimmune disease].
Diagnosis of systemic autoimmune diseases, including systemic lupus erythematosus (SLE), can be supported by detection of antinuclear antibodies (ANA). Additional support may be provided by detecting antibodies against...
Methodological quality of cohort study on rheumatic diseases in China: A systematic review.
To evaluate systematically the quality of the cohort studies on rheumatic diseases in China.Relevant databases were searched to find cohort studies on rheumatic diseases in China, and the basic information included in the...
Demodex positive discoid lupus erythematosus: Is it a separate entity or an overlap syndrome?
Discoid lupus erythematosus (DLE) is a chronic inflammatory erythematous skin disease that can be triggered by several factors. Rosacea is another skin disease that causes facial redness and tenderness. Demodex mites have been...
