Jul 15, 2021

Fisetin is a bioactive flavonol that inhibits osteoclastogenesis and promotes osteoblastogenesis. However, the osteogenic activity of fisetin needs to be comprehensively elucidated. In the present stu...

Jul 15, 2021

Immune system function changes during aging, but the molecular mechanisms of this phenomenon are not fully understood. The present study identified pathways that are associated with age-associated cha...

Jul 15, 2021

Pain in the musculoskeletal system and in the joints is what comes to mind first when people talk about rheumatic diseases. However, rheumatic diseases are multisystem disorders that can affect every ...

Jun 28, 2021

Circulating microRNAs (c-miRs) show promise as biomarkers. This systematic review explores their potential association with age-related fracture/osteoporosis (OP), osteoarthritis (OA) and sarcopenia (...

Jun 10, 2021

Osteoporosis is the process of bone loss, particular after menopause, when the production of estrogen in women is decreaing. Bioenergetic function is one of the critical roles in bone remodeling. Dang...

May 13, 2021

Shared decision making (SDM) in knee osteoarthritis (OA) is essential to optimizing patient-centered care and involves clinicians and patients collaborating to make decisions using the best available ...

May 06, 2021

Osteoporosis (OP) is an age-related disease characterized by reduced bone mass and increased bone fragility. It is more common in older people and postmenopausal women. As a new type of exercise train...

Mar 18, 2021

Prevalent vertebral fractures (PVFx) and abdominal aortic calcification (AAC) are both associated with incident fractures and can be ascertained on the same lateral spine images, but their joint assoc...

Jan 01, 2021

Tibial shaft fractures are one of the most common types of long bone fractures and are often managed by intramedullary nailing. Low-intensity pulsed ultrasound (LIPUS) and sham treatment are the two c...

Nov 06, 2020

Although previous studies indicate that HIV is a risk factor for missed menstrual periods, or amenorrhea, the downstream effects of amenorrhea and its associated hormonal dysregulation in these women ...

Oct 19, 2020

Total knee arthroplasty is a procedure commonly used to treat end-stage osteoarthritis of the knee. However, the success rate of the therapy is questionable as a large number of patients are at risk o...

Sep 24, 2020

Three years of high-dose vitamin D supplementation (400 IU, 4000 IU, 10,000 IU) in healthy vitamin D-sufficient individuals aged 55 to 70 years, resulted in a negative dose-response relationship for b...

Sep 11, 2020

Ankle sprains are one of the most common types of musculoskeletal injuries. Physiotherapy is routinely given to patients with ankle sprains. This study aims to evaluate the efficacy of supervised phys...

Sep 11, 2020

The American Association of Clinical Endocrinologists (AACE) and American College of Endocrinology (ACE) Clinical Practice Guidelines for the Diagnosis and Treatment of Postmenopausal Osteoporosis - 2...

Sep 11, 2020

Women with H. pylori infection were more likely to be older and have a higher body mass index (BMI) than those without H. pylori infection. Women with Helicobacter pylori (H. pylori) infection ar...

Sep 10, 2020

Achilles tendinopathy (AT), or Achilles tendinitis, is an injury of the Achilles tendon, which connects the calf muscle to the heel bone. The usual care given to patients with AT does not result in po...

Sep 03, 2020

Evidence indicates that ankle fractures are becoming increasingly more common among older people, presenting a significant burden to the US healthcare system, with annual costs exceeding $17 billion f...

Aug 31, 2020

Postmenopausal osteoporosis is a bone disease characterized by the loss of too much bone from the body after menopause. Odanacatib is a cathepsin K inhibitor that reduces bone resorption and maintains...

Aug 27, 2020

Venous leg ulceration is the most common type of leg ulcer in which veins in the leg stop working. Aspirin, an acetylsalicylic acid drug, is considered to be an adjuvant treatment for venous leg ulcer...

Aug 10, 2020

“Primary hyperparathyroidism (PHPT)-related osteoporosis is one of the most frequent causes of secondary osteoporosis, and it frequently occurs in postmenopausal women, with a prevalence of up to 1%...