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Osteoporosis

Immunomodulatory benefits of mesenchymal stem cells treated with Caffeine in adjuvant-induced arthritis.

Feb 13, 2020

We intend to assess the effect of the conditioned medium of Caffeine pulsed MSCS in the amelioration of rheumatoid arthritis (RA)-afflicted rats.MSCs were incubated with 0, 0.1, 0.5 or 1 mM Caffeine...

Is Bone Non-Union, Vertebral Deformity, or Spino-Pelvic Malalignment the Best Therapeutic Target for Amelioration of Low Back Pain after Osteoporotic Vertebral Fracture?

Feb 13, 2020

Cohort study (level 3).To identify independent risk factors for residual low back pain (LBP) following osteoporotic vertebral fracture (OVF).Non-union has been proposed as the primary cause of residua...

The combined association of depressive symptoms and C-reactive protein for incident disease risk up to 12 years later. Findings from the English Longitudinal of Ageing (ELSA).

Jan 24, 2020

Depression and inflammation are interrelated, and both are associated with the development of long-term conditions (LTCs). We investigated whether the combination of elevated depressive symptoms and e...

A reliable time-series method for predicting arthritic disease outcomes: New step from regression toward a nonlinear artificial intelligence method.

Jan 24, 2020

The interrupted time-series (ITS) concept is performed using linear regression to evaluate the impact of policy changes in public health at a specific time. Objectives of this study were to verify, wi...

A network pharmacology approach to explore the potential targets underlying the effect of sinomenine on rheumatoid arthritis.

Jan 24, 2020

To explore the potential targets underlying the effect of sinomenine (SIN) on rheumatoid arthritis (RA) by utilizing a network pharmacology approach.SIN and its drug targets were identified using netw...

Prediction of triptolide targets in rheumatoid arthritis using network pharmacology and molecular docking.

Jan 24, 2020

Network pharmacology is a novel approach that uses bioinformatics to predict and identify multiple drug targets and interactions in disease. Here, we used network pharmacology to investigate the mecha...

Comparison of Pediatric Familial Mediterranean Fever Patients Carrying Only E148Q Variant With the Ones Carrying Homozygous Pathogenic Mutations.

Jan 24, 2020

The aims of this study were to compare demographic data, clinical features, and severity scores of familial Mediterranean fever patients carrying E148Q variant with the patients having homozygous path...

PATIENT PERSPECTIVES ON OBESITY MANAGEMENT: NEED FOR GREATER DISCUSSION OF BMI AND WEIGHT-LOSS OPTIONS BEYOND DIET AND EXERCISE ESPECIALLY IN PATIENTS WITH DIABETES.

Jan 23, 2020

: To identify perceptions of obesity management in patients with and without diabetes. A 48-question survey was administered in 2018 to our Endocrinology Clinic's adult patients with a body mass inde...

Identification of PIEZO1 polymorphisms for human bone mineral density.

Jan 23, 2020

Bone mineral density (BMD) is a key indicator for diagnosis and treatment for osteoporosis; the reduction of BMD could increase the risk of osteoporotic fracture. It was very recently found that Piezo...