Exploring the Association Between ILD and Anti–SSA-52
The following is a summary of “Relationship between anti–SSA-52 and interstitial lung disease,” published in April 2024, issue of Rheumatology by Saunders et al. Despite the pro...
Osteoporosis Therapeutic Spotlight
Authoritative medical articles, news, research, and guidelines pertaining to Osteoporosis Therapeutic Spotlight.
MiR-98-5p Mitigates IL-1β-Induced Chondrocyte Injury in Osteoarthritis by Targeting CASP3
The following is a summary of “MiR-98-5p plays suppressive effects on IL-1β-induced chondrocyte injury associated with osteoarthritis by targeting CASP3,” published in the April 2024 is...
PROMs as Important as Disease Activity Indexes for Assessing PsA
New findings show that PROMs were strongly associated with several PsA activity indexes, and are as important as disease activity indexes for assessing PsA....
New method to differentiate between lupus anticoagulants, progressive coagulation inhibitors and coagulation factor deficiencies in the mixing tests.
Mixing tests in activated partial thromboplastin time (APTT) are used for the differentiation between lupus anticoagulants (LA), coagulation inhibitors, and factor deficient samples with APT...
Hematopoietic Stem Cell Transplantation Post-Myeloablation Leads to Longterm Normalization of Systemic Sclerosis Molecular Signatures
The following is a summary of “Myeloablation followed by hematopoietic stem cell transplantation leads to long-term normalization of systemic sclerosis molecular signatures,” published i...
Proteins and Pathways Identified for Intervertebral Disc Degeneration Development
The following is a summary of “Tandem Mass Tag-Based Proteomic Analysis of Normal and Degenerated Human Intervertebral Discs,” published in the March 2024 issue of Pain by Fu et al. ...
Noncriteria Antiphospholipid Antibodies Research Necessary for Diagnosis and Risk Stratification in Antiphospholipid Syndrome
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by thrombotic manifestations and/or obstetric complications in patients with persistently positive antiphospholipid ant...
Refined Animal Models May Improve Neuropsychiatric Systemic Lupus Erythematosus Management
Systemic lupus erythematosus (SLE) poses formidable challenges due to its multifaceted etiology while impacting multiple tissues and organs and displaying diverse clinical manifestations. Ge...
Q&A: How PsA Disease Activity Differs By Race & Ethnicity
New research suggests patients with psoriatic arthritis may experience the disease differently depending on their race and ethnicity....
Rheumatology High BP Protocol Reduces Disparities; Delays Remain for External Primary Care
The following is a summary of “Rheumatology high blood pressure protocol reduces disparities, but delays remain for external primary care,” published in the April 2024 issue of Rheumatol...
Association Between Anti-CCP Antibody Status & Polyautoimmunity in Rheumatoid Arthritis
The following is a summary of "Polyautoimmunity in Patients With Anticyclic Citrullinated Peptide Antibody–Positive and –Negative Rheumatoid Arthritis: A Nationwide Cohort Study From Den...
Early Intervention With Digital Self-Management Programs Crucial for Patients With Osteoarthritis
The following is a summary of “Weekly pain trajectories among people with knee or hip osteoarthritis participating in a digitally delivered first-line exercise and education treatment,” ...
Patients & HCPs Approve of Immune-Suppressing Treatment Risk-Based Monitoring for Adults With Inflammatory Diseases
The following is a summary of "Patient and health professional views on risk-stratified monitoring of immune-suppressing treatment in adults with inflammatory diseases," published in the Mar...
Evaluating the Safety and Effectiveness of Telitacicept in Treating Primary Sjögren’s Syndrome
The following is a summary of "Efficacy and safety of telitacicept in primary Sjögren’s syndrome: a randomized, double-blind, placebo-controlled, phase 2 trial," published in the March 20...
Gaps Persist for Link Between Depression & PsA
Depression impacted treatment decisions and outcomes in patients with psoriatic arthritis, according to recent findings....
Assessing MIS Posterior Fusion LinQ Allograft Implant for Sacroiliac Joint Dysfunction
The following is a summary of “Safety, Efficacy, and Durability of Outcomes: Results from SECURE: A Single Arm, Multicenter, Prospective, Clinical Study on a Minimally Invasive Posterior S...
Assessing the Value of MRI & Whole Exome Sequencing for Multicentric Carpotarsal Osteolysis Diagnosis
The following is a summary of “Multicentric carpotarsal osteolysis syndrome with variants of MAFB gene: a case report and literature review,” published in the March 2024 issue of Pediatr...
Rheumatic Diseases Impact Reproductive Health
Rheumatic diseases have a broad impact on reproductive success and pregnancy outcomes, according to a study published online March 20 in Rheumatology. Anne M. Kerola, M.D., Ph.D., from He...
Pain Challenges in Rheumatology: Variability in Case Definitions Using EHR-Based Chronic Pain Phenotyping Algorithms
The following is a summary of "Problem of Pain in Rheumatology: Variations in Case Definitions Derived From Chronic Pain Phenotyping Algorithms Using Electronic Health Records," published in...
Machine Learning Stratifies Immunophenotypes in MCTD, Validating Clinical Heterogeneity
The following is a summary of "Machine learning-driven immunophenotypic stratification of mixed connective tissue disease corroborating the clinical heterogeneity," published in the March 20...
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