Maximizing the Power of Artificial Intelligence in Neurosurgery by Expanding Real-World Use
Artificial Intelligence (AI) has permeated virtually every industry of the world, accelerating...
Neurosurgery
miR-26a Attenuated Bone-Specific Insulin Resistance and Bone Quality in Diabetic Mice.
Diabetes mellitus is a prevalent disease result in several complications, including bone problems. Previous studies have shown that microRNA (miR)-26a regulates glucose metabolism and plays a protective role in diabetes....
Monocyte-derived dendritic cells display a highly activated phenotype and altered function in patients with familial Mediterranean fever.
Dendritic cells (DCs) are sentinels of the immune system that bridge innate and adaptive immunity. By capturing antigens in peripheral tissue, processing and presenting them with concurrent expression of costimulatory molecules...
Comparison of the skin microbiota in acne and rosacea.
Acne and rosacea, despite their similar clinical presentations, follow distinct clinical courses, suggesting that fundamental differences exist in their pathophysiology. We performed a case-control study profiling the skin...
Combination of cyclic nucleotide modulators with P2Y receptor antagonists as anti-platelet therapy.
Endothelium-derived prostacyclin and nitric oxide elevate platelet cyclic nucleotide levels and maintain quiescence. We previously demonstrated a synergistic relationship exists between cyclic nucleotides and P2Y receptor...
Peer-to-Peer Contact Tracing: A Privacy-Preserving Smartphone Application.
The novel coronavirus disease 2019 (COVID-19) pandemic is an urgent public health crisis, with epidemiologic models predicting severe consequences, including high death rates, if the virus is permitted to run its course without...
Clotrimazole reduces endometriosis and the estrogen concentration by downregulating aromatase.
This study aimed to analyse the effects of clotrimazole (CTZ) on estrogen production pathway in endometriosis progression. Experimental endometriosis was induced by autologous transplantation in female Wistar rats, and then the...
A robust and novel electrical impedance metric of pulmonary function in ALS patients.
Pulmonary function tests (PFTs) are important for assessing respiratory function in amyotrophic lateral sclerosis (ALS) patients. However, weakness of oral and glottal closure, due to concomitant bulbar dysfunction, may result...
Enhanced transcutaneous electrical nerve stimulation achieved by a localized virtual bipole: A computational study of human tibial nerve stimulation.
Electrical neuromodulation is a clinically effective therapeutic instrument, currently expanding into newer indications and larger patient populations. Neuromodulation technologies are also moving towards less invasive...
The Clinical Significance of Seminoma Component in Testicular Mixed Germ Cell Tumour.
The aim of this study was to examine clinical/pathological characteristics, prognosis and tendency to metastasis of mixed germ cell tumours (MGCTs) that contain a seminoma component.A total of 111 MGCT cases between 2008 and...
Real-world clinical diagnostics of heart failure patients with reduced or preserved ejection fraction.
The study aimed at investigating the use of guideline-recommended diagnostic tools and medication in patients with heart failure (HF) in specialty care in Southwest Finland. We also compared the characteristics of the diagnosed...
Assessment of sidestream end-tidal capnography in ventilated infants on the neonatal unit.
Continuous monitoring of carbon dioxide (CO ) levels can be achieved by capnography. Our aims were to compare the performance of a sidestream capnograph with a low dead space and sampling rate to a mainstream device and evaluate...
