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Neurosurgery

Spatiotemporal signal detection using continuous shrinkage priors.

Feb 28, 2020

Periodontal disease (PD) is a chronic inflammatory disease that affects the gum tissue and bone supporting the teeth. Although tooth-site level PD progression is believed to be spatio-temporally refer...

ZNF687 mutations in an extended cohort of neoplastic transformations in Paget's disease of bone: implication for clinical pathology.

Feb 28, 2020

Neoplastic transformation is a rare but serious complication of Paget's disease of bone (PDB), occurring in fewer than 1% of individuals with polyostotic disease. Their prognosis is poor, with less th...

Ionizing radiation modulates vascular endothelial growth factor expression through STAT3 signaling pathway in rat neonatal primary astrocyte cultures.

Feb 28, 2020

Radiation-induced brain injury (RBI) usually occurs six months to three years after irradiation, often shows cognitive dysfunction, epilepsy, and other neurological dysfunction. In severe cases, it ca...

Radiprodil, a NR2B negative allosteric modulator, from bench to bedside in infantile spasm syndrome.

Feb 28, 2020

Infantile spasm syndrome (ISS) is an epileptic encephalopathy without established treatment after the failure to standard of care based on steroids and vigabatrin. Converging lines of evidence indicat...

Natural polyphenols in preclinical models of epilepsy.

Feb 18, 2020

Natural polyphenols are being tested both in preclinical and clinical settings for the treatment of different neurological disorders. The article describes the outcome of three polyphenols, resveratro...

Early growth outcomes in very low birth weight infants with bronchopulmonary dysplasia or fetal growth restriction.

Feb 18, 2020

To assess the growth outcomes at 18 months corrected age in very low birth weight (VLBW) infants compared to standardized norms, and in VLBW infants with and without bronchopulmonary dysplasia (BPD) o...

Overdose, Relapse After Buprenorphine Discontinuation High

Dec 27, 2019

The longer patients continue with buprenorphine treatment, the lower their risk of adverse outcomes.   THURSDAY, Dec. 26, 2019 (HealthDay News) -- Buprenorphine treatment may be needed ...