Evaluating Functional Status After Pediatric Continuous Kidney Replacement Therapy
Continuous kidney replacement therapy (CKRT) is used in the pediatric ICU (PICU) to support...
Transplantation
Defining and predicting progression in non-IPF interstitial lung disease.
Randomized placebo-controlled trials demonstrated the efficacy of antifibrotic treatment in non-IPF progressive fibrosing ILD (fILD). Currently, there is no consensus on how progression should be defined and clinical data of...
Effects of serum from mismatched patients with solid organ transplantation on the activation of microvascular cultures isolated from adipose tissues.
Aggregating the human leukocyte antigen (HLA) Class I antigens on the endothelial membrane has been known to elicit an activation, an underlying mechanism of chronic rejection in organ transplant recipients. The current study...
Clinical impact of complement deposition findings on biopsies in acute rejection episodes of pediatric renal transplant patients.
Rejection is the most important problem for renal graft function and survival. Complement system plays a key role in immune responses from host to graft. It was demonstrated that complement system activation is related with...
A Systematic Review of Multiple Linear Regression-Based Limited Sampling Strategies for Mycophenolic Acid Area Under the Concentration-Time Curve Estimation.
One approach of therapeutic drug monitoring in the case of mycophenolic acid (MPA) is a limited sampling strategy (LSS), which allows the evaluation of the area under the concentration-time curve (AUC) based on few...
Antibody-Mediated Rejection in Adult Liver Transplant Recipients: A Case Series and Literature Review.
Antibody-mediated rejection is a rare complication following liver transplantation and there is a lack of a comprehensive treatment strategy to provide detailed information about the dose and duration of antibody-mediated...
Microscope-Assisted Arterial Anastomosis in Adult Living Donor Liver Transplantation: A Systematic Review and Meta-analysis of Outcomes.
Living donor liver transplantation (LDLT) has expanded the availability of liver transplant but has been associated with early technical complications including the devastating complication of hepatic artery thrombosis (HAT),...
How I Do It: Considering lung transplantation for patients with COVID-19.
The COVID-19 pandemic has caused acute lung injury in millions of individuals worldwide. Some patients develop COVID-related acute respiratory distress syndrome (CARDS) and cannot be liberated from mechanical ventilation. Others...
ALF on the transplant waitlist: acetaminophen both better and worse?
Acute liver failure (ALF) is a critical illness whose study and treatment is complicated by its rarity, severity and phenotypic heterogeneity. For many years the cause of ALF has been recognised as a key determinant of its...
Impact of low-level pretransplant donor-specific antibodies on outcomes after kidney transplantation.
The effect of low-level pretransplant donor-specific antibody (DSA) on kidney transplant outcomes is not well described. The goal of this study was to compare outcomes among patients of varying immunologic risk, based on the...
Donor KIR Gene Content and KIR-Ligand Matching and Outcomes of Pediatric Patients with JMML Following Unrelated Donor Transplant.
Natural killer (NK) cell determinants predict relapse-free survival after allogeneic hematopoietic cell transplant (HCT) for acute myeloid leukemia, and prior studies show a beneficial graft versus leukemia effect in juvenile...
Human herpes virus 6 DNAemia is associated with worse survival after ex vivo T-cell depleted hematopoietic cell transplant.
We examined the correlation between persistent HHV-6 DNAemia (p-HHV-6) and absolute lymphocyte counts (ALC), platelet counts (PLT) and all-cause mortality the 1-year after ex vivo T-cell depleted (TCD) hematopoietic cell...
