Kardiologia polska 2017 10 05() doi 10.5603/KP.a2017.0177
We aimed to investigate the predictive value of the CHA₂DS₂-VASc score in the development of Contrast Induced Nephropathy (CIN).
A total of 2972 patients who had been diagnosed with ST elevation-MI and who had undergone primary coronary angioplasty were included in the study. The patients were divided into 3 groups according to the CHA₂DS₂-VASc score as low risk (1 point), intermediate risk (2 points) and high risk (≥3 points). The groups were followed-up with regard to CIN development.
The median CHA₂DS₂-VASc score was significantly higher in the CIN(+) groups compared to the CIN(-) group (3 vs 2, p<0.001). The rate of CIN was 3.32-fold higher in the high-risk group (CHA₂DS₂-VASc ≥3) compared to the low-risk group (CHA₂DS₂-VASc =1) (OR 3.32, p<0.001). Age (OR: 1.25, p<0.001), female gender (OR: 1.52, p<0.001), hypertension (OR: 1.50, p<0.001), peak CKMB (OR: 1.15, p<0.001) and the KILLIP score >1 (OR: 4.25, p<0.001) were found to be independent predictors for CIN development. CONCLUSIONS
The CHA₂DS₂-VASc score is an independent and strong predictor of CIN development in patients with acute ST-elevation MI.