To determine the association between the presence of cilioretinal arteries and the macular vasculature in highly myopic eyes using optical coherence tomography angiography (OCTA).
Retrospective, observational case series.
481 highly myopic eyes of 481 patients.
Fundus photographs were reviewed to determine the presence of a cilioretinal artery and its distribution, based on whether its path or visible branches reached the region within 500 μm of the foveal center. The macular vasculature was analyzed in OCTA images, including the vessel density (VD), fractal dimension (FD), and foveal avascular zone (FAZ). The associations between the presence of a cilioretinal artery and its distribution, and the macular vasculature and visual acuity were evaluated.
Cilioretinal arteries, macular vasculature, and their associations.
Of the eyes included, 17.05% (82/481) had a cilioretinal artery. Based on the OCTA analysis, the eyes with cilioretinal arteries showed significantly higher VD and FD in both superficial and deep capillary plexuses and smaller FAZ than those without (all P 30 mm. Eyes with cilioretinal arteries that reached the central foveal area showed significantly higher VD and FD in both capillary plexuses and smaller FAZ than those that did not (all P < 0.05). Better best-corrected visual acuity was identified in the eyes with cilioretinal arteries than in those without (0.09 ± 0.14 vs 0.21 ± 0.27, respectively; P < 0.001). In particular, eyes with cilioretinal arteries that reached the central foveal area had better visual acuity than those without (0.05 ± 0.06 vs 0.16 ± 0.20, respectively; P = 0.005).
This OCTA-based study suggested that cilioretinal arteries in highly myopic eyes might potentially improve the macular vasculature and influence the visual function.

Copyright © 2020. Published by Elsevier Inc.

References

PubMed