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Clinical and microbiologic characteristics of pleuro-pulmonary infection due to Streptococcus intermedius.

Clinical and microbiologic characteristics of pleuro-pulmonary infection due to Streptococcus intermedius.
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Cobo F, Sampedro A, Rodríguez-Granger J, Aliaga-Martínez L, Navarro-Marí JM,


Cobo F, Sampedro A, Rodríguez-Granger J, Aliaga-Martínez L, Navarro-Marí JM, (click to view)

Cobo F, Sampedro A, Rodríguez-Granger J, Aliaga-Martínez L, Navarro-Marí JM,

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Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 2018 03 22() pii

Abstract

The clinical and microbiological characteristics of pleuro-pulmonary infection (PPI) caused by Streptococcus intermedius is described, including 6 cases in the literature and 9 cases handled at the present centre. Out of the 15 patients, 12 were male; mean age at diagnosis was 62.06 ± 15 years. Twelve had risk factors for S. intermedius infection such as alcoholism in 5 (35.7%) patients, periodontal disease in 3 (24.6%) cases, chronic obstructive pulmonary disease in 3 (24.6%), and diabetes mellitus in 2 (14.2%). Cough was present in 12 (80%) patients and chest pain and dyspnea in 9 (60%). The mean diagnosis interval was 34 days. The diagnosis was obtained from pleural fluid aspirate in 13 (86.6%) cases and from biopsy/tissue samples in 2. The most frequently antimicrobials used for treatment were ceftriaxone + levofloxacin. Ten patients cured with a combination of medical and surgical treatment and 2 patients died as a consequence of infection. The incidence of PPI caused by S. intermedius is increasing in our health area; drainage along with antibiotic therapy is recommended for treatment.

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