Crohn’s disease (CD) can have an influence on a patient’s quality of life (QOL) in physical, social, and psychological ways. The purpose of this study was to look at the quality of life of children with CD and how it relates to patient and illness variables. This cross-sectional study, which took place in 35 French paediatric institutions, was open to children aged 10 to 17 who had been diagnosed with CD for more than 6 months. The IMPACT-III questionnaire was used to measure QOL. The characteristics of the patient and the illness were gathered. A total of 218 youngsters, with a median age of 14 years, were involved in the study. The median duration of CD was 3.2 years, and wPCDAI determined that 63 percent of children were in clinical remission. The IMPACT-III total score was 62.8. The lowest score was in the area of “emotional functioning.” Clinical remission was the most important independent factor related to children with CD’s QOL. The age of the patient at the time of the examination was shown to be adversely associated with QOL. The total IMPACT-III score and its subcategories were not associated with gender, illness duration, or therapies.

These findings not only indicate that clinical remission is a key concern for patients’ QOL, but also emphasise the need of psychological treatment.