Septal perforation closure is still often invasive and complex, with relatively low closure rates.

We aimed to provide the first results of a case series of 20 patients with nasal septal perforations who underwent septal perforation repair by both an open and a minimally invasive technique by using a graft that consisted of temporoparietal fascia and a PDS plate without mucosal flaps. 

The septal perforations were closed by insertion of a graft, which consisted of a 0.25-mm PDS flexible plate enveloped by temporoparietal fascia into the perforation. No attempts were made to close the perforation by mucosal flap rotation and advancement. Protective plastic sheeting to both sides of the perforation provided fixation to the graft, while natural mucosal healing occurred over the perforation in the course of 3 to 8 weeks.

For the first time, we showed that the insertion of a graft that consisted of a PDS flexible plate enveloped in temporoparietal fascia via a hemitransfixion incision was feasible and resulted in complete mucosal closure of nasal septal perforations in most patients. By performing the hemitransfixion incision, we avoided any visible nasal scars.