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Comparison of the ACC/AHA and Framingham algorithms to assess cardiovascular risk in HIV-infected patients.

Comparison of the ACC/AHA and Framingham algorithms to assess cardiovascular risk in HIV-infected patients.
Author Information (click to view)

Neto LFDSP, Dias FR, Bressan FF, Santos CRO,


Neto LFDSP, Dias FR, Bressan FF, Santos CRO, (click to view)

Neto LFDSP, Dias FR, Bressan FF, Santos CRO,

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The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 2017 07 18() pii S1413-8670(16)30494-9
Abstract

The aim of this study was to compare the predictions of Framingham cardiovascular (CV) risk score (FRS) and the American College of Cardiology/American Heart Association (ACC/AHA) risk score in an HIV outpatient clinic in the city of Vitoria, Espirito Santo, Brazil. In a cross-sectional study 341 HIV infected patients over 40 years old consecutively recruited were interviewed. Cohen’s kappa coefficient was used to assess agreement between the two algorithms. 61.3% were stratified as low risk by Framingham score, compared with 54% by ACC/AHA score (Spearman correlation 0.845; p<0.000). Only 26.1% were classified as CV high risk by Framingham compared to 46% by ACC/AHA score (Kappa=0.745; p<0.039). Only one out of eight patients had CV high risk by FRS at the time of a myocardial infarction event registered up to five years before the study period. Both CV risk scores but especially FRS underestimated CV high-risk patients in this HIV-infected population.

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