The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 2017 07 18() pii 10.1016/j.bjid.2017.06.007
The aim of this study was to compare the predictions of Framingham cardiovascular (CV) risk score (FRS) and the American College of Cardiology/American Heart Association (ACC/AHA) risk score in an HIV outpatient clinic in the city of Vitoria, Espirito Santo, Brazil. In a cross-sectional study 341 HIV infected patients over 40 years old consecutively recruited were interviewed. Cohen’s kappa coefficient was used to assess agreement between the two algorithms. 61.3% were stratified as low risk by Framingham score, compared with 54% by ACC/AHA score (Spearman correlation 0.845; p<0.000). Only 26.1% were classified as CV high risk by Framingham compared to 46% by ACC/AHA score (Kappa=0.745; p<0.039). Only one out of eight patients had CV high risk by FRS at the time of a myocardial infarction event registered up to five years before the study period. Both CV risk scores but especially FRS underestimated CV high-risk patients in this HIV-infected population.