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Considerations for sustainable influenza vaccine production in developing countries.

Considerations for sustainable influenza vaccine production in developing countries.
Author Information (click to view)

Nannei C, Chadwick C, Fatima H, Goldin S, Grubo M, Ganim A,


Nannei C, Chadwick C, Fatima H, Goldin S, Grubo M, Ganim A, (click to view)

Nannei C, Chadwick C, Fatima H, Goldin S, Grubo M, Ganim A,

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Vaccine 2016 Sep 734(45) 5425-5429 pii S0264-410X(16)30743-5
Abstract

Through its Global Action Plan for Influenza Vaccines (GAP), the World Health Organization (WHO) in collaboration with the United States Department of Health and Human Services has produced a checklist to support policy-makers and influenza vaccine manufacturers in identifying key technological, political, financial, and logistical issues affecting the sustainability of influenza vaccine production. This checklist highlights actions in five key areas that are beneficial for establishing successful local vaccine manufacturing. These five areas comprise: (1) the policy environment and health-care systems; (2) surveillance systems and influenza evidence; (3) product development and manufacturing; (4) product approval and regulation; and (5) communication to support influenza vaccination. Incorporating the checklist into national vaccine production programmes has identified the policy gaps and next steps for countries involved in GAP’s Technology Transfer Initiative. Lessons learnt from country experiences provide context and insight that complement the checklist’s goal of simplifying the complexities of influenza prevention, preparedness, and vaccine manufacturing.

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