For a study, researchers sought to evaluate the likelihood of CAC>0 and create age-sex-race percentiles for 30-45-year-old people in the United States. To research CAC in 19,725 asymptomatic Black and White persons aged 30-45 years with no known atherosclerotic cardiovascular disease, combined three datasets: CARDIA (Coronary Artery Risk Development in Young Adults), the CAC Consortium, and the Walter Reed Cohort. Nonparametric approaches were used to assess the likelihood of CAC>0 and the age-sex-race percentiles of CAC distributions after equally weighting each cohort.
CAC>0 was found in 26% of White men, 16% of Black males, 10% of White females, and 7% of Black females. All girls with CAC>0 were automatically put in the 90th percentile. CAC>0 placed White guys in the 90th percentile at age 34 years, whereas Black males were in the 37th percentile. An interactive portal allowed you to enter your age, gender, race, and CAC score to get an estimated percentile.
The chance of CAC >0 varied by age, gender, and race in a large sample of US people aged 30-45 years without symptomatic atherosclerotic cardiovascular disease. Estimated percentiles may aid in the understanding of CAC scores among young people in comparison to their age-sex-race matched peers and will be included in CAC score reporting going forward.