COVID-19 vaccination is not associated with fecundability among couples trying to conceive, according to a study published in the American Journal of Epidemiology. Amelia K. Wesselink, MPH, and colleagues examined the associations of COVID-19 vaccination and SARS-CoV-2 infection with fertility among couples trying to conceive spontaneously. A total of 2,126 selfidentified women were enrolled from December 2020 to September 2021 and were followed through November 2021. Questionnaires on sociodemographics, lifestyle, medical factors, and partner information were completed every 8 weeks. Researchers found that COVID-19 vaccination was not appreciably associated with fecundability in women or men (female fecundability ratio [FR], 1.08; 95% CI, 0.95-1.23; male FR, 0.95; 95% CI, 0.83-1.10). There was no association for female SARS-CoV-2 infection with fecundability (FR, 1.07; 95% CI, 0.87-1.31), while male infection was associated with a transient reduction in fecundability (FR, 0.82; 95% CI, 0.47-1.45) for infection within 60 days and (FR, 1.16; 95% CI, 0.92-1.47) for infection at least 60 days prior.
