DBS for Treatment-Resistant Depression


Chronic subcallosal cingulate deep brain stimulation (DBS) appears to be safe and effective for the long term in individuals with treatment resistant depression (TRD). A team of American researchers found that 2 years of active DBS resulted in remission of TRD in 58% of patients. A response after DBS occurred in 92% of patients with TRD during the study period. The authors added that spontaneous relapse was not experienced by any patients who achieved remission.

Abstract: Archives of General Psychiatry, January 2, 2012.


  1. Am interested to be evaluated for DBS surgery



  1. Deep Brain Stimulation & Depression | Physician's Weekly - [...] Nearly all patients experienced some improvement in depression severity, with most achieving remis­sion after 2 years of SCC DBS.…

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