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December 2017 Briefing – Pediatrics

December 2017 Briefing – Pediatrics
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Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for December 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Atopic Dermatitis Associated With Higher Risk of Skin Cancer

THURSDAY, Dec. 28, 2017 (HealthDay News) — Atopic dermatitis (AD) is associated with an increased risk of developing squamous cell carcinoma (SCC), according to a study published online Dec. 15 in the International Journal of Dermatology.

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Urogenital Health Issues Seen in Girls Years After Sexual Abuse

THURSDAY, Dec. 28, 2017 (HealthDay News) — Girls sexually abused in childhood have more urinary and genital health problems, even years after the abuse, than those in the general population, according to a study published online Dec. 15 in The Journal of Pediatrics.

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Criteria Developed for Idiopathic Inflammatory Myopathies

THURSDAY, Dec. 28, 2017 (HealthDay News) — New classification criteria have been developed for idiopathic inflammatory myopathies (IIM), according to an article published in the December issue of Arthritis & Rheumatology.

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Sleep May Mediate Fish-Cognition Relationship in Children

THURSDAY, Dec. 28, 2017 (HealthDay News) — Greater fish consumption is associated with fewer sleep problems and higher IQ scores in children, with sleep quality partially mediating the relationship between fish consumption and verbal IQ, according to a study published online Dec. 21 in Scientific Reports.

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Neuroanatomic Abnormalities ID’d in Those at Risk for Autism

THURSDAY, Dec. 28, 2017 (HealthDay News) — Neuroanatomic abnormalities are seen in cohorts at high risk for autism spectrum disorder (ASD), according to a study published in the January issue of Radiology.

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Psychosocial Risk in Teens Tied to Lasting HIV Vulnerability

THURSDAY, Dec. 28, 2017 (HealthDay News) — High-frequency psychosocial risk factors during adolescence have a lasting effect on the likelihood of engaging in HIV risk behaviors in adulthood, according to a study published online Dec. 12 in AIDS.

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2009 to 2016 Saw Increase in Prenatal Marijuana Use

WEDNESDAY, Dec. 27, 2017 (HealthDay News) — Prenatal marijuana use increased from 2009 to 2016 for pregnant women of all ages, according to a research letter published in the Dec. 26 issue of the Journal of the American Medical Association.

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Weak Association for Blood Lead Levels, Criminal Behavior

WEDNESDAY, Dec. 27, 2017 (HealthDay News) — Childhood blood lead level (BLL) is a poor discriminator between criminal conviction and no conviction, according to a study published online Dec. 26 in JAMA Pediatrics.

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L. reuteri DSM17938 Effective for Colic in Breastfed Infants

WEDNESDAY, Dec. 27, 2017 (HealthDay News) — Lactobacillus reuteri DSM17938 is effective for breastfed infants with colic, according to a meta-analysis published online Dec. 26 in Pediatrics.

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Risk of ESRD in T1DM Patients Has Fallen Markedly in Finland

WEDNESDAY, Dec. 27, 2017 (HealthDay News) — The cumulative risk of end-stage renal disease (ESRD) among patients with type 1 diabetes has declined over time in Finland, according to a study published online Dec. 20 in Diabetes Care.

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Early Menarche May Affect Mental Health in Adulthood

TUESDAY, Dec. 26, 2017 (HealthDay News) — Girls with menarche at earlier ages may be at elevated risk for mental health issues in adolescence that carry into adult years, according to a study published online Dec. 26 in Pediatrics.

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FDA Removes Boxed Warning From Certain Asthma Medications

TUESDAY, Dec. 26, 2017 (HealthDay News) — New evidence regarding safety is spurring the U.S. Food and Drug Administration to remove a Boxed Warning from certain inhaled medications used to treat asthma and chronic obstructive pulmonary disease.

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Text Message Interventions May Help With Weight Management

TUESDAY, Dec. 26, 2017 (HealthDay News) — Extended-contact, text-message-delivered interventions appear to be effective for weight management, according to a review published online Dec. 15 in Obesity Reviews.

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Good Long-Term Survival After Childhood Liver Transplant

TUESDAY, Dec. 26, 2017 (HealthDay News) — Liver transplantation in childhood is associated with good long-term survival, according to a study published online Dec. 15 in the American Journal of Transplantation.

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Bone Fragility Variants Linked to Concordant Pediatric Skeleton

THURSDAY, Dec. 21, 2017 (HealthDay News) — Established bone fragility variants are associated with a concordant phenotypic model of the pediatric skeleton but not with discordant phenotypic models, according to a study published online Dec. 14 in the Journal of Bone and Mineral Research.

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Early-Stage Cancer Diagnoses Up With ACA’s Medicaid Expansions

THURSDAY, Dec. 21, 2017 (HealthDay News) — In their first year, the 2014 Medicaid expansions, facilitated by the Affordable Care Act, were associated with an increase in cancer diagnoses, particularly at the early stage, according to a study published online Dec. 21 in the American Journal of Public Health.

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Obesity Tied to Greater Asthma Impairment in Preschoolers

THURSDAY, Dec. 21, 2017 (HealthDay News) — For preschool children, overweight/obesity is associated with more asthma symptom days and exacerbations among those not treated with a daily controller, and inhaled corticosteroids (ICS) are associated with significant improvements among overweight/obese preschoolers, according to research published online Dec. 19 in the Journal of Allergy and Clinical Immunology.

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Methotrexate, Azathioprine Seem Safe Long-Term for Dermatitis

THURSDAY, Dec. 21, 2017 (HealthDay News) — Methotrexate and azathioprine appear to be effective and safe as maintenance treatments in moderate-to-severe atopic dermatitis for up to five years, according to research published online Dec. 13 in the British Journal of Dermatology.

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Microneedling Plus TCA Peel Performs Well in Acne Scarring

WEDNESDAY, Dec. 20, 2017 (HealthDay News) — Microneedling combined with trichloroacetic acid (TCA) peeling is more effective than microneedling by dermaroller plus platelet-rich plasma (PRP) or microneedling alone for treatment of acne scarring, according to a study published online Dec. 10 in the Journal of Cosmetic Dermatology.

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Narrow-Spectrum Antibiotics Best for Children With Acute RTIs

TUESDAY, Dec. 19, 2017 (HealthDay News) — For children with acute respiratory tract infections, broad-spectrum antibiotics are not associated with better clinical or patient-centered outcomes compared with narrow-spectrum antibiotics, according to a study published in the Dec. 19 issue of the Journal of the American Medical Association.

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Special Precautions Not Advised for Flu Vaccine in Egg Allergic

TUESDAY, Dec. 19, 2017 (HealthDay News) — Inactivated influenza vaccine (IIV) and live attenuated influenza vaccine (LAIV) are safe for individuals with egg allergy of any severity, according to a practice parameter update published online Dec. 19 in the Annals of Asthma, Allergy & and Immunology.

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Primary Care Crucial for Preventing New HIV Infections

TUESDAY, Dec. 19, 2017 (HealthDay News) — Primary care providers will play an important role in preventing the next wave of HIV infections, according to a report published in Medical Economics.

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RA Exposure In Utero Tied to Increased Disease Risk

TUESDAY, Dec. 19, 2017 (HealthDay News) — Children born to mothers with rheumatoid arthritis may have an increased risk of rheumatoid arthritis, thyroid disease, and epilepsy, according to a study published online Dec. 11 in Arthritis Care & Research.

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Equation Predicts Risk of End-Stage Renal Disease in Children

MONDAY, Dec. 18, 2017 (HealthDay News) — The kidney failure risk equation (KFRE) is a simple tool that provides excellent discrimination of the risk of end-stage renal disease (ESRD) in children with chronic kidney disease (CKD), according to a study published online Dec. 18 in JAMA Pediatrics.

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Male U.S. Doctors Receive Higher Values of Industry Payments

MONDAY, Dec. 18, 2017 (HealthDay News) — Male physicians in the United States received higher values of general payments from industry than females in 2015, according to a research letter published online Dec. 18 in JAMA Internal Medicine.

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Payment for Laboratory Tests Set to Reduce Starting Jan. 1, 2018

MONDAY, Dec. 18, 2017 (HealthDay News) — The Centers for Medicare & Medicaid Services (CMS) has released the Clinical Laboratory Fee Schedule, which is set to reduce payments for testing services conducted in physician office-based laboratories, according to a report published by the American Medical Association (AMA).

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Counseling Linked to Reduction in Vaccine Exemption Rates

MONDAY, Dec. 18, 2017 (HealthDay News) — Implementation of Washington state’s Senate Bill 5005 (SB5005), which requires counseling and a signed form from a licensed health care provider to obtain a vaccine exemption, was associated with a decrease in exemption rates and an increase in vaccine coverage for vaccines required for school entrance, according to a study published online Dec. 18 in Pediatrics.

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Probiotics, Chewing Gum Found Ineffective for Pharyngitis

MONDAY, Dec. 18, 2017 (HealthDay News) — Neither probiotics nor xylitol-based chewing gum cuts the severity of symptoms associated with pharyngitis, according to a study published in the Dec. 18 issue of CMAJ, the journal of the Canadian Medical Association.

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Anaphylaxis Is Rare Complication of Pregnancy

MONDAY, Dec. 18, 2017 (HealthDay News) — Anaphylaxis is a rare complication of pregnancy, with an estimated incidence of 1.6 per 100,000 maternities, according to a study published online Nov. 29 in BJOG: An International Journal of Obstetrics and Gynaecology.

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Year One Results Out for Value-Based Payment Modifier Program

MONDAY, Dec. 18, 2017 (HealthDay News) — Almost 30 percent of eligible practices failed to register and report data in the first year of the Physician Value-Based Payment Modifier program, according to a report published in the December issue of Health Affairs.

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Long-Term Macrolide Use Linked to Resistant P. Acnes

MONDAY, Dec. 18, 2017 (HealthDay News) — Long-term oral macrolide administration may increase macrolide-resistant Propionibacterium acnes, according to a study published online Dec. 13 in the Journal of Dermatology.

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Doctors Must Report on at Least 1 Patient, 1 Measure for MACRA

FRIDAY, Dec. 15, 2017 (HealthDay News) — In order to meet the 2017 Medicare and CHIP Reauthorization Act (MACRA) participation reporting deadline and avoid a Medicare payment penalty in 2019, physicians must report on at least one patient and one measure by Dec. 31, and submit to Medicare no later than Feb. 28, 2018, according to a report from the American Medical Association (AMA).

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Functional Limitations Ongoing With Congenital Zika

FRIDAY, Dec. 15, 2017 (HealthDay News) — Severe functional limitations are reported among children with microcephaly and laboratory evidence of Zika virus infection in infancy, according to research published in the Dec. 15 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.

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Flu Vaccine Expected to Protect Against Most U.S. H3N2 Viruses

FRIDAY, Dec. 15, 2017 (HealthDay News) — A novel bioinformatics approach can predict vaccine effectiveness for the influenza season, and indicates that the current vaccines are likely to be effective against H3N2 flu viruses in the U.S. 2017/2018 flu season, according to research published online Nov. 29 in F1000 Research.

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Making Insurers Participate in Marketplace Could Cut Volatility

THURSDAY, Dec. 14, 2017 (HealthDay News) — Requiring insurers that participate in Medicare or Medicaid to also participate in Marketplaces in the same geographic area could improve access to insurance, according to a study published in the December issue of Health Affairs.

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Bivalent Meningococcal B Vaccine Safe, Immunogenic

THURSDAY, Dec. 14, 2017 (HealthDay News) — A bivalent meningococcal B vaccine targeting factor H-binding protein (MenB-FHbp) elicits bactericidal responses against diverse meningococcal B strains after two and three doses in adolescents and young adults, according to a study published in the Dec. 14 issue of the New England Journal of Medicine.

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Breathing Retraining Beneficial in Patients With Asthma

THURSDAY, Dec. 14, 2017 (HealthDay News) — A breathing retraining intervention, delivered digitally or via face-to-face sessions, can improve quality of life in patients with asthma, according to a study published online Dec. 13 in The Lancet Respiratory Medicine.

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Day-Care Centers Have More Allergens Than Homes

THURSDAY, Dec. 14, 2017 (HealthDay News) — Mite, mouse, cat, and dog allergens are higher in day-care centers (DCCs) than in homes, according to a study published online Nov. 29 in Allergy.

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Serum Homocysteine Higher in Acne Patients

THURSDAY, Dec. 14, 2017 (HealthDay News) — Acne patients have higher levels of serum homocysteine (HCY), according to a study published online Nov. 21 in the Journal of Cosmetic Dermatology.

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Stricter Short-Term Glycemic Control May Increase Remission

THURSDAY, Dec. 14, 2017 (HealthDay News) — Stricter glycemic control during short-term intensive insulin therapy for newly diagnosed type 2 diabetes patients is associated with a higher likelihood of remission at one year, according to a study published online Nov. 30 in the Journal of Diabetes Investigation.

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In Utero Methylphenidate Exposure Tied to Heart Defects

WEDNESDAY, Dec. 13, 2017 (HealthDay News) — Intrauterine exposure to methylphenidate is associated with a small increase in the risk of cardiac malformations, according to a study published online Dec. 13 in JAMA Psychiatry.

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Amount of Opioids Prescribed After Hospital Discharge Varies

WEDNESDAY, Dec. 13, 2017 (HealthDay News) — For postoperative patients there is considerable variation in the amount of opioids prescribed at hospital discharge, according to research published online Dec. 13 in JAMA Surgery.

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Omalizumab Ups Efficacy of Multifood Oral Immunotherapy

TUESDAY, Dec. 12, 2017 (HealthDay News) — Omalizumab improves the efficacy of multifood oral immunotherapy among pediatric patients with multifood allergies, according to a study published online Dec. 12 in The Lancet Gastroenterology & Hepatology.

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Pediatric Oncologists Willing to Consider Medical Marijuana

TUESDAY, Dec. 12, 2017 (HealthDay News) — The absence of standards is an important barrier to pediatric oncologists recommending medical marijuana (MM), despite their willingness to do so, according to a study published online Dec. 12 in Pediatrics.

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Window Blinds Continue to Pose Injury Risk for Young Children

MONDAY, Dec. 11, 2017 (HealthDay News) — The rate of window blind-related injuries among children younger than 6 years of age treated in U.S. emergency departments is 2.7 per 100,000 children, according to a study published online Dec. 11 in Pediatrics.

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Preconception Paternal SSRI Use Linked to ADHD in Offspring

MONDAY, Dec. 11, 2017 (HealthDay News) — Paternal use of selective serotonin reuptake inhibitors (SSRIs) before conception is associated with increased risk of attention-deficit/hyperactivity disorder (ADHD) in offspring, according to a study published online Dec. 11 in Pediatrics.

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Deceleration in Health Care Spending Growth in 2016

MONDAY, Dec. 11, 2017 (HealthDay News) — Health care spending growth slowed in 2016 following faster growth in 2014 and 2015, according to research published online Dec. 6 in Health Affairs.

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Prenatal Sugar Intake May Increase Asthma Risk in Offspring

FRIDAY, Dec. 8, 2017 (HealthDay News) — Increased maternal prenatal and early childhood intake of sugar-sweetened beverages and fructose is associated with increased odds of developing childhood asthma, according to a study published online Dec. 8 in the Annals of the American Thoracic Society.

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Influenza Picking Up in U.S., Predominantly A(H3N2)

FRIDAY, Dec. 8, 2017 (HealthDay News) — Influenza activity was low during October 2017 but started increasing in November, with influenza A, predominantly A(H3N2), most commonly identified, according to research published in the Dec. 8 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report.

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Moving More May Match Focused Exercise in Prediabetes

THURSDAY, Dec. 7, 2017 (HealthDay News) — The accumulation of total physical activity (PA) over the day may be as important as achieving the intensity of moderate-to-vigorous PA (MVPA) for improved cardiometabolic health of adults with prediabetes, according to a study published online Nov. 20 in Diabetes Care.

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Guideline-Adherent Assessment of Nonaccidental Trauma Up

WEDNESDAY, Dec. 6, 2017 (HealthDay News) — An improvement methodology can increase guideline-adherent evaluation for patients with provider concern for nonaccidental trauma (NAT) in the pediatric emergency department, according to research published online Dec. 6 in Pediatrics.

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State Newborn Screening Policies Cut Infant Cardiac Deaths

TUESDAY, Dec. 5, 2017 (HealthDay News) — Implementation of state newborn screening policies for critical congenital heart disease is associated with a decrease in infant cardiac deaths, according to a study published in the Dec. 5 issue of the Journal of the American Medical Association.

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Acute Intermittent Porphyria Described in Teen Girl

TUESDAY, Dec. 5, 2017 (HealthDay News) — A case of a 16-year-old presenting to the emergency department with acute intermittent porphyria (AIP) is described in a case report published online Dec. 5 in Pediatrics.

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CVS-Aetna Merger Has Implications for Doctors’ Offices

TUESDAY, Dec. 5, 2017 (HealthDay News) — CVS Health’s planned purchase of insurance giant Aetna, a $69 billion deal, was announced Sunday.

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Spatial Variation in Psychosis Incidence in Rural Areas

MONDAY, Dec. 4, 2017 (HealthDay News) — In rural areas, there is spatial variation in the incidence of nonaffective and affective psychotic disorders, according to a study published online Nov. 29 in JAMA Psychiatry.

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Risk of Persistent Opioid Use a Concern for Youth After Surgery

MONDAY, Dec. 4, 2017 (HealthDay News) — Adolescents and young adults are at risk for persistent opioid use after surgery, and this represents an important pathway to consider in the epidemic of prescription opioid misuse, according to a study published online Dec. 4 in Pediatrics.

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>40% of Cancers, Cancer Deaths Due to Modifiable Risk Factors

FRIDAY, Dec. 1, 2017 (HealthDay News) — An estimated 42.0 percent of all incident cancers and 45.1 percent of cancer deaths in the United States are attributed to potentially modifiable risk factors, according to a study published online Nov. 21 in CA: A Cancer Journal for Clinicians.

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Lower Microbial Diversity in the Gut in Anorexia Nervosa

FRIDAY, Dec. 1, 2017 (HealthDay News) — Females with anorexia nervosa (AN) have lower gut microbial diversity, according to a study published online Nov. 13 in the International Journal of Eating Disorders.

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Network Density Not Linked to Response in Teen Depression

FRIDAY, Dec. 1, 2017 (HealthDay News) — Adolescents with depression who are poor responders to treatment do not have more densely connected networks, according to a research letter published online Nov. 29 in JAMA Psychiatry.

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