Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for December 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Three Novel Loci Associated With Polycystic Ovary Syndrome ID’d

MONDAY, Dec. 31, 2018 (HealthDay News) — Three novel loci have been identified for polycystic ovary syndrome (PCOS), according to research published online Dec. 19 in PLOS Genetics.

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Incidence of End-Stage Kidney Disease Up in Australia

MONDAY, Dec. 31, 2018 (HealthDay News) — For nonindigenous people with type 2 diabetes mellitus (T2DM) in Australia, the age-standardized incidence of end-stage kidney disease (ESKD) increased from 2002 to 2013, according to a study published online Dec. 19 in the American Journal of Kidney Diseases.

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Second-Line Antidiabetic Meds May Impact Cardiovascular Risk

FRIDAY, Dec. 28, 2018 (HealthDay News) — For adults with type 2 diabetes initiating second-line antidiabetic medications (ADM), cardiovascular risk is increased with use of sulfonylureas or basal insulin versus newer ADM classes, according to a study published online Dec. 21 in JAMA Network Open.

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Pregnancy Complications Up for Women Born at Low Birth Weight

FRIDAY, Dec. 28, 2018 (HealthDay News) — Women born with a low birth weight have an increased risk for pregnancy complications, according to a study published online Dec. 19 in Obesity.

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Sugar-Sweetened Drinks Linked to Chronic Kidney Disease Risk

FRIDAY, Dec. 28, 2018 (HealthDay News) — A pattern of higher consumption of sugar-sweetened beverages is associated with increased odds of chronic kidney disease (CKD), according to a study published online Dec. 27 in the Clinical Journal of the American Society of Nephrology.

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Targeted Muscle Reinnervation Can Reduce Phantom Limb Pain

THURSDAY, Dec. 27, 2018 (HealthDay News) — Use of primary targeted muscle reinnervation (TMR) can prevent or reduce pain in below-the-knee amputees, according to a report published online Dec. 27 in Plastic and Reconstructive Surgery.

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Low-Priced Generic Drugs Most Likely to Have Shortages

THURSDAY, Dec. 27, 2018 (HealthDay News) — The lowest-priced generic drugs are more likely to experience shortages, according to a study published in the November issue of Value in Health.

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Initiative Can Cut Gender Gap in Medical School Faculty Salaries

WEDNESDAY, Dec. 26, 2018 (HealthDay News) — An institutional gender equity initiative (GEI) can reduce gender-based salary gaps among medical school faculty, according to a study published online Dec. 21 in JAMA Network Open.

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ACOG: Interpregnancy Period Should Maximize Women’s Health

WEDNESDAY, Dec. 26, 2018 (HealthDay News) — Providers should maximize women’s health during the interpregnancy period, continuing care beyond the immediate postpartum period, according to a consensus report published online Dec. 20 in the American Journal of Obstetrics & Gynecology.

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FDA Warns Companies on Unsafe, Unapproved Stem Cell Treatments

FRIDAY, Dec. 21, 2018 (HealthDay News) — After infections tied to unapproved stem cell treatments sent 12 people to the hospital this past year, the U.S. Food and Drug Administration has issued a stern warning about the products.

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CDC: Weight, Waist Size, BMI Increased for Many U.S. Adults

FRIDAY, Dec. 21, 2018 (HealthDay News) — From 1999-2000 to 2015-2016, there was an increase in mean weight, waist circumference, and body mass index (BMI) for many U.S. adults, according to the Dec. 20 issue of the National Vital Statistics Reports, a publication from the U.S. Centers for Disease Control and Prevention.

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Affordable Care Act Sign-Ups Higher Than Expected

THURSDAY, Dec. 20, 2018 (HealthDay News) — Despite numerous difficulties, early figures show that sign-ups for health coverage next year under the Affordable Care Act are higher than expected.

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Growth in Use of Telemedicine Seen From 2005 to 2017

THURSDAY, Dec. 20, 2018 (HealthDay News) — From 2005 to 2017, there was a substantial increase in telemedicine use, although use was still uncommon in 2017, according to a research letter published online Nov. 27 in the Journal of the American Medical Association.

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ADA 2019 Standards of Care Emphasize Patient-Centered Care

THURSDAY, Dec. 20, 2018 (HealthDay News) — Patient-centered care is emphasized in updated clinical practice recommendations from the American Diabetes Association 2019 Standards of Care, published as a supplement to the January issue of Diabetes Care.

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Endocrine Tx Does Not Impair Neuropsychological Performance

WEDNESDAY, Dec. 19, 2018 (HealthDay News) — For early-stage breast cancer survivors, endocrine therapy (ET) appears to have no effect on neuropsychological performance or impairment over six years of follow-up, according to a study published online Nov. 28 in Cancer.

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Failure of Timely Stop to Certain Prescription Drugs Is Common

WEDNESDAY, Dec. 19, 2018 (HealthDay News) — Legacy prescribing of certain drugs, such as antidepressants and proton pump inhibitors (PPIs), is common, according to a study published in the November/December issue of the Annals of Family Medicine.

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Exclusion of Doctors From Public Health Insurance Up 2007 to 2017

TUESDAY, Dec. 18, 2018 (HealthDay News) — From 2007 to 2017, the number of physicians excluded from Medicare and state public insurance programs increased, according to a study published online Dec. 14 in JAMA Network Open.

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Type 2 Diabetes Risk Lower in Women With Active Migraine

MONDAY, Dec. 17, 2018 (HealthDay News) — Women with active migraine have a lower risk for type 2 diabetes, according to a study published online Dec. 17 in JAMA Neurology.

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Some With Type 2 Diabetes Inappropriately Monitoring Blood Glucose

MONDAY, Dec. 17, 2018 (HealthDay News) — A considerable proportion of patients with type 2 diabetes may be self-monitoring blood glucose inappropriately, according to a research letter published online Dec. 10 in JAMA Internal Medicine.

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Prevalence of Metabolically Healthy Adults in U.S. Very Low

MONDAY, Dec. 17, 2018 (HealthDay News) — Very few U.S. adults are metabolically healthy, according to a study published online Nov. 27 in Metabolic Syndrome and Related Disorders.

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T2DM Linked to Decline in Verbal Memory, Fluency in Older Adults

FRIDAY, Dec. 14, 2018 (HealthDay News) — Type 2 diabetes is associated with declines in verbal memory and fluency among older community-dwelling adults, according to a study published online Dec. 13 in Diabetologia.

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Persistent Discrimination ID’d Among Physician Mothers

FRIDAY, Dec. 14, 2018 (HealthDay News) — Physician mothers experience discrimination in a range of ways, which can impact the medical profession, according to a study published online Dec. 12 in The BMJ.

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Medication Errors Resulting in Death Most Common in Elderly

THURSDAY, Dec. 13, 2018 (HealthDay News) — Medication errors in acute care that result in death occur most often in patients older than 75 years, with the most common error category being omitted medicine or ingredient, according to a study published online Nov. 22 in Research in Social and Administrative Pharmacy.

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Risk for Hospitalization for Heart Failure Greater With Diabetes

THURSDAY, Dec. 13, 2018 (HealthDay News) — Despite declining incidence, heart failure hospitalization is increased among individuals with diabetes, according to a study published in the Dec. 11 issue of Circulation.

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Negative Attitudes Reported Toward Weight-Loss Surgery

THURSDAY, Dec. 13, 2018 (HealthDay News) — A large proportion of the U.S. population seems to have negative attitudes toward weight-loss surgery, according to a research letter published online Dec. 12 in JAMA Surgery.

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Enrollment Under the Affordable Care Act Down From Last Year

WEDNESDAY, Dec. 12, 2018 (HealthDay News) — Enrollment for health insurance under the Affordable Care Act is down with just days left to sign up, according to the U.S. Centers for Medicare & Medicaid Services.

AP News Article

2017 Saw Slowing in National Health Care Spending

WEDNESDAY, Dec. 12, 2018 (HealthDay News) — National health care spending slowed in 2017, according to a report published online Dec. 6 in Health Affairs.

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Young Breast Cancer Patients Face Higher Risk for Osteoporosis

WEDNESDAY, Dec. 12, 2018 (HealthDay News) — The risk for bone loss rises sharply in young breast cancer patients who received standard treatment, according to a study recently published in Breast Cancer Research.

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Fasting-Evoked Hypoglycemia in Diabetes Is Prevalent

WEDNESDAY, Dec. 12, 2018 (HealthDay News) — About 17 percent of patients with diabetes report experiencing hypoglycemia when fasting for lab tests, according to a study recently published in the International Journal of Endocrinology.

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Paid Childbearing Policies Lacking for Residents

TUESDAY, Dec. 11, 2018 (HealthDay News) — Policies for paid childbearing or family leave for residents are lacking at top-ranking medical schools and may be exacerbated by lack of direction from specialty boards, according to two research letters published in the Dec. 11 issue of the Journal of the American Medical Association.

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U.S. Medical Schools See Increase in Diversity

TUESDAY, Dec. 11, 2018 (HealthDay News) — After implementation of the Liaison Committee on Medical Education (LCME) diversity accreditation standards, U.S. medical schools saw increasing percentages of female, black, and Hispanic matriculants, according to a research letter published in the Dec. 4 issue of the Journal of the American Medical Association.

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Consensus Decision Pathway Developed for Tobacco Cessation

TUESDAY, Dec. 11, 2018 (HealthDay News) — An expert consensus decision pathway has been developed for tobacco cessation treatment; the report was published online Dec. 5 in the Journal of the American College of Cardiology.

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HIT-Related Stress Linked to Burnout Among Physicians

MONDAY, Dec. 10, 2018 (HealthDay News) — Stress related to use of health information technology (HIT) is common and predictive of burnout among physicians, according to a study published online Dec. 5 in the Journal of the American Medical Informatics Association.

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AHA Scientific Statement: Low Risk of Side Effects for Statins

MONDAY, Dec. 10, 2018 (HealthDay News) — Statins are associated with a low risk for side effects, according to a scientific statement from the American Heart Association (AHA) published online Dec. 10 in Arteriosclerosis, Thrombosis and Vascular Biology.

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Less Than One Hour of Resistance Training Weekly Tied to Lower CVD Risk

MONDAY, Dec. 10, 2018 (HealthDay News) — Less than an hour a week of resistance exercise (RE) is associated with decreased risks for cardiovascular disease (CVD)-related events and all-cause mortality, independent of aerobic exercise, according to a study recently published in Medicine & Science in Sports & Exercise.

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Most Insured Patients Not Using Online Portals

FRIDAY, Dec. 7, 2018 (HealthDay News) — Nearly two-thirds of insured adults with a previous health care visit did not use an online patient portal in 2017, according to a study published in the December issue of Health Affairs.

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Fear Impacts Quality of Life for Young Adults With Type 1 Diabetes

FRIDAY, Dec. 7, 2018 (HealthDay News) — Fear of complications and frustration at the amount of time required to manage type 1 diabetes impact the quality of life of young adults with the disease, according to a study published in the December issue of The Diabetes Educator.

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Chronic Kidney Disease Burden Increasing in the United States

FRIDAY, Dec. 7, 2018 (HealthDay News) — The burden of chronic kidney disease (CKD) increased in the United States between 2002 and 2016, although there was variability by state, according to a study published online Nov. 30 in JAMA Network Open.

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Patient Education Can Improve Chronic Disease Management

FRIDAY, Dec. 7, 2018 (HealthDay News) — An educational intervention can improve patients’ ability to self-manage their chronic diseases, according to a study published in the November issue of the Journal of the American Osteopathic Association.

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Lack of Peds Preventive Care Ups Unplanned Hospital Admissions

FRIDAY, Dec. 7, 2018 (HealthDay News) — A lack of preventive care in infants and children is associated with an increased rate of unplanned hospital admissions, according to a study recently published in BMC Medicine.

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Type 2 Diabetes Linked to Colorectal Cancer Risk in Men

WEDNESDAY, Dec. 5, 2018 (HealthDay News) — Type 2 diabetes (T2D) is associated with an increased risk for colorectal cancer (CRC), with the association significant for men only, according to a study published online Nov. 7 in the British Journal of Cancer.

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Skin Autofluorescence Predicts T2DM, Heart Disease, Mortality

WEDNESDAY, Dec. 5, 2018 (HealthDay News) — Skin autofluorescence predicts incident type 2 diabetes, cardiovascular disease (CVD), and mortality in the general population, according to a study published online Nov. 21 in Diabetologia.

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Few Physicians Work in Practices That Use Telemedicine

WEDNESDAY, Dec. 5, 2018 (HealthDay News) — Only 15.4 percent of physicians work in practices that use telemedicine for a wide spectrum of patient interactions, with larger practice size being an important correlate of telemedicine use, according to a study published in the December issue of Health Affairs.

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Many Patients Withhold Information From Clinicians

TUESDAY, Dec. 4, 2018 (HealthDay News) — Many patients intentionally withhold information from clinicians, according to a study published online Nov. 30 in JAMA Network Open.

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HHS Issues Draft Strategy for Reducing Health IT Burden

TUESDAY, Dec. 4, 2018 (HealthDay News) — The U.S. Department of Health and Human Services has developed a draft strategy to reduce the health information technology (IT) burden, and the strategy is open for public comment through Jan. 28, 2019.

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Exposure to Phthalates May Impact Timing of Puberty in Girls

TUESDAY, Dec. 4, 2018 (HealthDay News) — Exposure to certain endocrine-disrupting chemicals may impact the timing of puberty in children, according to a study published online Dec. 4 in Human Reproduction.

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Cost-Related Insulin Underuse May Affect One in Four Patients

MONDAY, Dec. 3, 2018 (HealthDay News) — About one in four patients report cost-related insulin underuse, which is associated with poor glycemic control, according to a research letter published online Dec. 3 in JAMA Internal Medicine.

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Impact of Fructose Varies With Energy Control, Food Source

MONDAY, Dec. 3, 2018 (HealthDay News) — Energy control and food source appear to mediate the effect of fructose-containing sugars on glycemic control, according to a review published online Nov. 21 in The BMJ.

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