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Decreased Hepatitis B vaccine response in pediatric patients with atopic dermatitis, psoriasis, and morphea.

Decreased Hepatitis B vaccine response in pediatric patients with atopic dermatitis, psoriasis, and morphea.
Author Information (click to view)

Patel DP, Treat JR, Castelo-Socio L,


Patel DP, Treat JR, Castelo-Socio L, (click to view)

Patel DP, Treat JR, Castelo-Socio L,

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Vaccine 2017 07 2035(35 Pt B) 4499-4500 pii 10.1016/j.vaccine.2017.07.025

Abstract

Multiple groups of patients have been recognized for having high rates of non-responders to the Hepatitis B vaccine including those with HIV, inflammatory bowel disease, and chronic kidney disease. These patients are at increased risk for infection due to both the nature of their underlying diseases and the immunosuppressive drugs they are commonly prescribed. Identification of groups with high non-response rates is essential in order to establish vaccination guidelines and prevent serious infections in already susceptible patients. We thus aimed to assess the rate of antibody response to the HBV vaccine in patients with psoriasis, atopic dermatitis, or morphea prior to starting immunosuppressive therapy.

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