The study was aimed to determine the diagnostic yield and outcome of transrectal ultrasound-guided prostate biopsy (TRUSPB) in a cohort of Sri Lankan men. A prospective study was conducted among 333 (median age: 70 years, range:48-88) men from a single urology unit. All patients underwent TRUSPB for persistently elevated serum prostate specific antigen (PSA)≥4.00 ng/mL or suspicious rectal examination. The prostate cancer (PCa) detection rate was 57.7%. The PCa detection rate for PSA levels of 4.00 to <10, 10.00 to <20, 20.00 to <40, 40.00 to <100 and ≥100.00 ng/mL were 15/43(34.9%), 23/88(26.1%), 41/72(56.9%), 51/63(81.0%) and 60/62(96.8%) respectively. Ten patients required further biopsies for rising PSA despite a first benign biopsy and three had PCa. Mild complications were identified in 6.9%(n=23). The high PCa detection rate probably reflects the difference in our policy to perform biopsies only when serum PSA level is persistently elevated. TRUSPB appears to have a satisfactory yield with acceptable level of complications in the Sri Lankan resource limited setting.
About The Expert
Umesh Jayarajah
Sanjeewa Vidanapathirana
Shinthujaa Mahadewa
Saranga Wijayagunawardena
Velayuthan Senthan
Kapila Edirisinghe
Madura Ambegoda
Anuruddha M Abeygunasekera
References
PubMed