To study and compare factors contributing to the differentiation of diagnosed and undiagnosed primary angle-closure glaucoma (PACG) and primary open-angle glaucoma (POAG) in the same population.
Population-based survey.
All residents aged 40 years and older in Kumejima, Japan.
PACG and POAG were diagnosed according to the criteria of the International Society of Geographical and Epidemiological Ophthalmology. Factors contributing significantly to the differentiation of diagnosed and undiagnosed PACG and POAG were selected from various systemic, ocular, visual functional and fundus planimetric parameters using multivariate logistic regression analysis and compared between the two diseases.
Factors contributing significantly to the differentiation of diagnosed and undiagnosed PACG and POAG.
The respective prevalence rates of PACG and POAG were 2.2% and 4.0%, respectively. A great proportion of PACG cases (34.1%) were previously diagnosed than POAG cases (17.2%, p= 0.004). Worse mean deviation on visual field testing (odds ratio 0.869, 95% confidence interval 0.788-0.959; p=0.006) and the presence of signs suggestive of previous acute angle closure (odds ratio, 4.35; range, 1.66-11.36; p=0.003) contributed to a established diagnosis of PACG at the time of screening. A greater vertical cup/disc ratio (3.74; range 1.38-10.17; p=0.012) contributed with marginal significance to an established diagnosis of POAG at the time of screening.
PACG was more likely to have been previously diagnosed than POAG during a screening exam. Examination of the anterior segment and visual field may contribute more to the detection of PACG and disc examination to the detection of POAG.

Copyright © 2021. Published by Elsevier Inc.