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Disseminated Mycobacterium genavense Infection in Patient with Adult-Onset Immunodeficiency.

Disseminated Mycobacterium genavense Infection in Patient with Adult-Onset Immunodeficiency.
Author Information (click to view)

Asakura T, Namkoong H, Sakagami T, Hasegawa N, Ohkusu K, Nakamura A,


Asakura T, Namkoong H, Sakagami T, Hasegawa N, Ohkusu K, Nakamura A, (click to view)

Asakura T, Namkoong H, Sakagami T, Hasegawa N, Ohkusu K, Nakamura A,

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Emerging infectious diseases 23(7) 1208-1210 doi 10.3201/eid2307.161677

Abstract

We report a case of disseminated Mycobacterium genavense infection resulting from neutralizing anti-interferon-γ autoantibodies in the patient. We identified M. genavense targeting the hsp65 gene in an aspiration specimen of the lymph node. Adult-onset immunodeficiency caused by neutralizing anti-interferon-γ autoantibodies, in addition to HIV infection, can lead to disseminated nontuberculous mycobacterial infection.

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