This study aims to investigate symptoms of dry eye and signs of ocular surface disease in children with myopia during OK lens wear.
A total of 68 subjects were prospectively managed with OK lens correction. These subjects were 8-14 years of age with myopia -0.50 to -5.00 dioptres of sphere and astigmatism of≤1.00 dioptres of cylinder. Patients with any ocular disease were ruled out from this study. All subjects completed a dry eye symptom questionnaire for OSDI scoring, corneal fluorescein staining, tear film break up time (TBUT) test and Schirmer’s test I during the follow-up period. The follow-up period includes the primary visit (baseline), and at one day, one week, one month and six months after wearing the lens.
In terms of dry eye symptoms, we found that OSDI scores were significantly high after one day of wearing the lens (P<0.05). Additionally, TBUT values significantly decreased after one day (P<0.01) and one week (P<0.05) of wearing the OK lens. Corneal staining grade also significantly increased after one day and one week of wearing the OK lens. Furthermore, Schirmer's Test I values slightly, but not significantly, increased after one day and one week of wearing the lens. All variables returned to pre-wear levels at one month after wearing the lens, which remained stable up to six months of wearing the OK lens.
Our study is the first reveal that OK lens wear in children leads to dry eye symptoms and disturbs the tear film during the initial period of OK lens wear. However, this did not significantly interfere with tear secretion during the follow-up period.

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