Small and nonsolid peripheral lung lesions are challenging to diagnose for surgeons and pulmonologists. Electromagnetic navigation bronchoscopy with dye tagging of these lesions may increase the surgeon’s capacity to resect by minimally invasive techniques. The researchers explained why dye marking through navigation bronchoscopy was used, as well as their preferred approach and case examples to show the procedure. In addition, a systematic literature search in PubMed was conducted using the phrases “navigation bronchoscopy,” “dye marking,” and “lung nodules,” and the results were reviewed. The researchers showed how to combine electromagnetic navigation bronchoscopy with methylene blue dye labeling of peripheral tiny and nonsolid lung lesions to properly designate nodules for easier excision. In addition, 10 retrospective case studies with a total of 257 individuals and 276 nodules were examined. 

The success rates for marking and excision of the lesion in issue ranged from 79% to 100%, with an average of 95%. There were no major pneumothoraces or hemothorax, and the complication rate was low. The use of electromagnetic navigation bronchoscopy-guided dye labeling of tiny and nonsolid peripheral lung nodules was a safe and accurate method of identifying these difficult-to-find lesions. Using these procedures increases the surgeon’s ability to resect difficult lesions with minimum risk of complications.