We evaluated EV-D68 the study of disease transmission and phylogenetics among kids matured ≤9 years hospitalized with extreme intense respiratory ailments at five locales in Panama and El Salvador during 2012-2013. Respiratory examples positive for enterovirus or rhinovirus were tried by ongoing RT-PCR for EV-D68, and fractional VP1 quality groupings were resolved. Of 715 selected youngsters, 17 from locales in the two nations were EV-D68-positive and regularly had a background marked by asthma or wheezing. Phylogenetically, 15 of 16 arrangements fell into Clade B1, and one into Clade A2. The Central American EV-D68s were firmly related hereditarily to contemporaneous strains from North America, South America, and the Caribbean. 

From the principal portrayal of enterovirus D68 (EV-D68) in 1962 until 2014, inconsistent cases and little bunches of EV-D68 respiratory infection were accounted for from around the globe. During 2014, a huge episode of EV-D68 happened in the United States and Canada, with more modest quantities of cases revealed in ensuing years.1-3 Few instances of EV-D68 are accounted for in the writing from Latin America before 2014.4, 5 During 2014, a flare-up of EV-D68 was accounted for from Mexico City; nonetheless, a boundless pestilence, like happened in the United States, was not documented.6 Additionally, during 2014, two EV-D68 cases were accounted for from Chile and four from two Caribbean islands.

Reference link- https://onlinelibrary.wiley.com/doi/10.1111/irv.12815