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Epidemiology of Type-1 diabetes in Polish children: a multicentre cohort study.

Epidemiology of Type-1 diabetes in Polish children: a multicentre cohort study.
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Szalecki M, Wysocka-Mincewicz M, Ramotowska A, Mazur A, Lisowicz L, Ben-Skowronek I, Sieniawska J, Klonowska B, Charemska D, Nawrotek J, Jałowiec I, Bossowski A, Jamiołkowska M, Pyrżak B, Miszkurka G, Szypowska A,


Szalecki M, Wysocka-Mincewicz M, Ramotowska A, Mazur A, Lisowicz L, Ben-Skowronek I, Sieniawska J, Klonowska B, Charemska D, Nawrotek J, Jałowiec I, Bossowski A, Jamiołkowska M, Pyrżak B, Miszkurka G, Szypowska A, (click to view)

Szalecki M, Wysocka-Mincewicz M, Ramotowska A, Mazur A, Lisowicz L, Ben-Skowronek I, Sieniawska J, Klonowska B, Charemska D, Nawrotek J, Jałowiec I, Bossowski A, Jamiołkowska M, Pyrżak B, Miszkurka G, Szypowska A,

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Diabetes/metabolism research and reviews 2017 11 16() doi 10.1002/dmrr.2962
Abstract
BACKGROUND
The incidence of childhood Type-1 diabetes (T1D) varies greatly between populations and the estimates and/or predictions of the rates would aid in adequate planning of health care resources. The study’s aim was to assess the incidence of T1D in the paediatric population of eastern and central Poland.

METHODS
In this cohort study covering the period from January 2010 to December 2014 data were collected for children and adolescents below 18 years of age with newly diagnosed T1D, living in eastern and central Poland. A total of 2174 children were included in the analysis. The population estimates were from the Central Statistical Office of Poland.

RESULTS
Overall, the annual incidence of T1D increased from 12.84/100 000 in 2010 to 18.46/100 000 in 2014 with the incidence rate ratio (IRR) of 1.5 (an increase in the incidence rate (IR) by 12.7% per year over 5 years). The lowest increase in the IR by 7.1% per year was seen in 15-17-year-olds. In the urban population (age 0-17 years), the overall IR was significantly higher than in subjects from rural communities (p<0.02). A statistically significant difference was demonstrated between the incidence of T1D in rural areas in densely populated voivodships vs less populated regions (p=0.004), but no such dependence in urban areas. CONCLUSIONS
The incidence of T1D in children living in eastern and central Poland increased 1.5-fold over the 5-year observation period with the highest rise in 10-14-year-olds and significantly higher rates in urban children compared to their peers living in rural areas.

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