Advertisement

 

 

Erythropoietin levels in patients with sleep apnea: a meta-analysis.

Erythropoietin levels in patients with sleep apnea: a meta-analysis.
Author Information (click to view)

Zhang XB, Zeng YM, Zeng HQ, Zhang HP, Wang HL,


Zhang XB, Zeng YM, Zeng HQ, Zhang HP, Wang HL, (click to view)

Zhang XB, Zeng YM, Zeng HQ, Zhang HP, Wang HL,

Advertisement
Share on FacebookTweet about this on TwitterShare on LinkedIn

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology – Head and Neck Surgery 2017 03 09() doi 10.1007/s00405-017-4483-1
Abstract

Currently available data regarding the blood levels of erythropoietin (EPO) in sleep apnea (SA) patients are contradictory. The aim of the present meta-analysis was to evaluate the EPO levels in SA patients via quantitative analysis. A systematic search of Pubmed, Embase, and Web of Science were performed. EPO levels in SA group and control group were extracted from each eligible study. Weight mean difference (WMD) or Standard mean difference (SMD) with 95% confidence interval (CI) was calculated by using fixed-effects or random effect model analysis according to the degree of heterogeneity between studies. A total of 9 studies involving 407 participants were enrolled. The results indicated that EPO levels in SA group were significantly higher than that in control group (SMD 0.61, 95% CI 0.11-1.11, p = 0.016). Significantly higher EPO levels were found in patients with body mass index <30 kg/m(2), and cardiovascular complications in the subsequent subgroup analysis (both p < 0.05). High blood EPO levels were found in SA patients in the present meta-analysis.

Submit a Comment

Your email address will not be published. Required fields are marked *

one × 2 =

[ HIDE/SHOW ]