Advertisement

 

 

Expression of YAP and TAZ in molluscum contagiosum virus infected skin.

Expression of YAP and TAZ in molluscum contagiosum virus infected skin.
Author Information (click to view)

Seo HM, Moon GT, Song YM, Gee HY, Park YM, Lee JY, Lee JH,


Seo HM, Moon GT, Song YM, Gee HY, Park YM, Lee JY, Lee JH, (click to view)

Seo HM, Moon GT, Song YM, Gee HY, Park YM, Lee JY, Lee JH,

Advertisement
Share on FacebookTweet about this on TwitterShare on LinkedIn

The British journal of dermatology 2018 01 12() doi 10.1111/bjd.16333
Abstract

The Hippo signaling pathway, which is highly conserved in organisms ranging from Drosophila to mammals, plays a key role in organ size control, cellular proliferation, survival and tumorigenesis1 Yes-associated protein (YAP) is the major downstream effector of Hippo signaling pathway and transcriptional co-activator with PDZ-binding motif (TAZ) is a YAP paralog. Recently, Zhang et al. found that YAP/TAZ acts as natural inhibitors of TANK binding kinase 1 (TBK1), which is a key component for cytosolic nucleic acid sensing antiviral defense and antiviral physiology2 This article is protected by copyright. All rights reserved.

Submit a Comment

Your email address will not be published. Required fields are marked *

3 × two =

[ HIDE/SHOW ]