To evaluate the ability of the liquid-injectable OdneFill sealer to stay within the boundaries of prepared root canals of posterior teeth using a cadaveric model.
Eight maxillary bone blocks containing 3 to 5 posterior teeth were collected. Pre-operative radiographs were taken, and only maxillary premolars (n = 10) and molars (n = 16) were included. The canals were prepared with WaveOne Gold Primary and Large instruments, then randomly assigned to two groups (n = 33 canals). Group 1 used Warm Vertical Compaction with gutta-percha and AH Plus sealer, while Group 2 used only the OdneFill sealer to fill the canals. Post-operative radiographs were taken to assess sealer extrusion into the periapical tissues using a 4-point scale. Data analysis was conducted with a 5% significance level.
Out of 26 teeth examined (5 teeth were excluded), 47.6% (8 molars and 2 premolars) showed filling extrusion, with 77.8% of teeth in Group 1 (12 root canals) and 25.0% in Group 2 (3 root canals). A significant difference was found in the frequency of sealer extrusion between the two groups (P = 0.001), but no significant difference was observed between premolars and molars in terms of sealer extrusion frequency (P = 0.144).
The OdneFill filling protocol showed better control over extrusion compared to the Warm Vertical Compaction technique in posterior teeth of a cadaveric model.
This study highlights the potential of a new liquid-injectable root canal sealer designed to remain confined within the boundaries of the root canal anatomy.

© 2025. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.